AFP DEPARTMENT COLLECTION

POEMs: Patient-Oriented Evidence that Matters

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Oct 1, 2019 Issue
e-Cigarettes More Effective Than Nicotine Replacement for Cessation of Tobacco Use in Adults
Among adults who smoked a median of 15 cigarettes per day, those who were randomized to receive e-cigarettes were more likely to be abstinent at one year than those who received nicotine replacement (number needed to treat [NNT] = 12).


Oct 1, 2019 Issue
Oral Antibiotics Are Equal to IV Antibiotics for Serous Bone and Joint Infections
Oral antibiotics started within seven days of surgery for patients with a serious bone or joint infection are as safe and effective as six weeks of IV antibiotics.


Oct 1, 2019 Issue
Pneumatic Compression in Addition to Pharmacologic Thromboprophylaxis Does Not Further Reduce DVT Risk
This study found no benefit to the addition of intermittent pneumatic compression to pharmacologic anticoagulation for the prevention of proximal DVT in critically ill patients.


Oct 1, 2019 Issue
Laboratory-Based Prediction Model Can Rule Out Serious Bacterial Infections in Febrile Infants
In febrile infants up to 60 days of age, the combination of a normal urinalysis result, an absolute neutrophil count of less than 4,090 per mL (4.1 × 109 per L), and a serum procalcitonin level of less than 1.71 ng per mL is accurate at ruling out serious bacterial infections.


Sep 15, 2019 Issue
Normal Vital Signs and Pulmonary Examination Results Rule Out CAP in Adults with Acute Respiratory Infection
Community-dwelling adults who present to a primary care office with acute respiratory infection symptoms but normal vital signs and normal findings on a pulmonary examination have only a 0.4% likelihood of community-acquired pneumonia (CAP).


Sep 15, 2019 Issue
Omega-3 Fatty Acids Do Not Prevent Cancer or Cardiovascular Disease Events
This is the second large, well-designed study (the first one included patients with diabetes mellitus; this one included patients without diabetes) that found no benefit from a 1-g daily dosage of marine n-3 fatty acid supplementation for the primary prevention of cardiovascular disease or cancer.


Sep 15, 2019 Issue
Vitamin D Is Not Effective as Primary Prevention of Cardiovascular Disease or Cancer
Vitamin D supplementation does not prevent cardiovascular events or cancer in mostly nondiabetic adults (men 50 years and older, women 55 years and older).


Sep 15, 2019 Issue
Weak Evidence Supports Augmentation Therapy for Treatment-Resistant Depression
There is weak research to guide treatment decisions for patients who have not responded to two adequate courses of antidepressant treatment. One study of cognitive behavior therapy showed benefit over placebo.


Aug 15, 2019 Issue
Short-Term Clopidogrel Plus Aspirin Prevents Second Ischemic Stroke Better Than Aspirin Alone
Combined treatment with clopidogrel and aspirin, started within 24 hours of the first event, will decrease the likelihood of a recurrent stroke in an additional 2% of patients compared with aspirin alone, with a slight increase in the risk of extra-cranial bleeding.


Aug 15, 2019 Issue
5% Fluorouracil Is the Preferred Treatment for Actinic Keratoses
The use of topical 5% fluorouracil is most likely to result in successful elimination of actinic keratoses in a field on the head or face.


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