AFP DEPARTMENT COLLECTION

POEMs: Patient-Oriented Evidence that Matters

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Aug 15, 2019 Issue
Short-Term Clopidogrel Plus Aspirin Prevents Second Ischemic Stroke Better Than Aspirin Alone
Combined treatment with clopidogrel and aspirin, started within 24 hours of the first event, will decrease the likelihood of a recurrent stroke in an additional 2% of patients compared with aspirin alone, with a slight increase in the risk of extra-cranial bleeding.


Aug 15, 2019 Issue
5% Fluorouracil Is the Preferred Treatment for Actinic Keratoses
The use of topical 5% fluorouracil is most likely to result in successful elimination of actinic keratoses in a field on the head or face.


Aug 1, 2019 Issue
More Evidence Against Antibiotics for Acute Asthma Exacerbations
Antibiotics do not benefit patients hospitalized with an asthma exacerbation. Evidence from this study suggests worse outcomes with antibiotic use, including a longer hospital stay, higher costs, and greater risk of diarrhea.


Aug 1, 2019 Issue
Dapagliflozin in High-Risk Type 2 Diabetes Reduces Hospitalization for Heart Failure But Does Not Reduce Death, Myocardial Infarction, or Stroke
The only cardiovascular benefit to treatment with dapagliflozin was a reduction in the likelihood of hospitalization; 125 patients would need to be treated for 10 years to prevent one hospitalization.


Jul 15, 2019 Issue
Misoprostol Alone is Associated with High Rate of Successful First-Trimester Abortion
Misoprostol alone was associated with a nearly 80% success rate in the first trimester of pregnancy on meta-analysis.


Jul 15, 2019 Issue
Vitamin D is Equal to Placebo for Preventing Cognitive Decline in African-American Women with Low Vitamin D Levels
Is vitamin D more effective than placebo in preventing cognitive decline in African American women older than 65 years who have low serum vitamin D levels at baseline?


Jul 15, 2019 Issue
Omega-3 Oil Does Not Reduce Serious Cardiovascular Events for Patients with Diabetes Mellitus
In this study, there was no significant difference in the likelihood of a composite vascular outcome or all-cause mortality in patients given an omega-3 fatty acid supplement compared with those given an olive oil placebo.


Jul 15, 2019 Issue
In Healthy Older Adults, Low-Dose Aspirin Increases All-Cause and Cancer-Specific Mortality
The findings are completely unexpected. Although recent studies by this group and other groups of researchers have failed to find a cardiovascular benefit, likely because of better control of other cardiovascular risk factors, this study found increased all-cause mortality, primarily due to increased cancer-related mortality.


Jun 1, 2019 Issue
Probiotic Ineffective for Treatment of Acute Gastroenteritis in Young Children


Jun 1, 2019 Issue
Aspirin, Eicosapentaenoic Acid, and Placebo Equally Effective in Preventing Colorectal Adenomas in High-Risk Patients
After 12 months, neither aspirin nor EPA, alone or in combination, are any better than placebo at preventing colorectal adenomas in patients with high-risk neoplasia.


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