POEMs: Patient-Oriented Evidence that Matters

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Aug 1, 2020 Issue
Rates of Adverse Effects of Treatment for Otitis Media Vary by Antibiotic and Dose
The rates of diarrhea and rashes associated with the treatment of children with acute otitis media vary depending on each specific antibiotic and its dosing. The rates of diarrhea and generalized rash were highest with amoxicillin/clavulanate (Augmentin) and high-dose amoxicillin, and lowest with azithromycin (Zithromax).

Jul 15, 2020 Issue
Increasing the D-dimer Threshold for Patients with Low Clinical Pretest Probability Effectively Rules Out PE
The Pulmonary Embolism Graduated d-Dimer strategy increases the number of patients in the emergency department and outpatient setting who have PE ruled out via d-dimer testing, thus decreasing the need for chest imaging.

Jul 15, 2020 Issue
Mailing gFOBT or FIT Directly to Patients Increases Uptake of Colorectal Cancer Screening
Mailed outreach significantly increases rates of colorectal cancer screening, with four tests needing to be mailed to screen one person.

Jul 15, 2020 Issue
No Cow's Milk Formula for the First Three Days of Life Prevents Food Allergies
In infants at increased risk of atopy, restricting cow's milk supplementation for the first three days of life is associated with a significantly lower risk of developing a cow's milk allergy or food allergies by 24 months of age.

Jul 15, 2020 Issue
Mind-Body Treatments Enhance Opioid Treatment of Patients with Acute or Chronic Pain
Using mindfulness, meditation, hypnosis, therapeutic suggestion, and cognitive behavior therapy, in addition to opioid treatment of acute or chronic pain, provides an additional benefit to patients by reducing pain scores.

Jun 1, 2020 Issue
Supplemental MRI Screening in Women with Very Dense Breasts Reduces Interval Cancer Rate but May Cause Overdiagnosis
Supplemental MRI screening for women with very dense breasts compared with mammography alone every two years significantly reduces the likelihood of an interval cancer, from 5 per 1,000 to 2.5 per 1,000 in the intention-to-treat population and to 0.8 per 1,000 in the per-protocol population.

Jun 1, 2020 Issue
Useful Signs and Symptoms for Diagnosing Hip Osteoarthritis
Although plain radiographs are often used to diagnose hip OA, the correlation between radiographic indicators of hip arthritis and hip pain is low.

Jun 1, 2020 Issue
No Short-Term Extra Benefit when Muscle Relaxants Are Added to Ibuprofen for Acute Low Back Pain
Adding a muscle relaxant to treatment with ibuprofen does not improve functional outcomes or pain, or lessen the number of people reporting moderate to severe back pain one week after starting treatment.

Jun 1, 2020 Issue
For Three-Vessel Disease, but Not Left Main Disease, CABG Is Preferred Over PCI
For patients with left main disease, PCI with a drug-eluting stent and CABG had similar all-cause mortality rates at 10 years. For those with three-vessel disease, CABG is associated with lower 10-year mortality.

May 15, 2020 Issue
Equivalent Pain Relief with Different Doses of Ibuprofen
Higher doses of ibuprofen for acute pain relief offer no more benefit at 60 minutes than a single 400-mg dose. The same has been shown for chronic treatment of osteoarthritis. A higher, anti-inflammatory dose is not needed.

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