AFP DEPARTMENT COLLECTION

POEMs

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Mar 15, 2019 Issue
Aspirin Plus a High-Dose PPI Prevents Death and Progression in Patients with Barrett Esophagus
In this study, patients with Barrett esophagus were less likely to die or develop esophageal cancer or high-grade dysplasia if they took high-dose esomeprazole (Nexium) alone or in combination with aspirin.


Mar 15, 2019 Issue
Gabapentin and Pregabalin Not Effective for Low Back Pain with or Without Radiculopathy
The use of anticonvulsants like gabapentin (Neurontin) for painful conditions has increased greatly in recent years. This review finds good evidence that these drugs are not an effective treatment for low back pain with or without radiculopathy, and are associated with an increased risk of adverse events.


Mar 15, 2019 Issue
Lorcaserin Is Safe, But Only Modestly Effective for Weight Loss
Lorcaserin, 10 mg twice daily, helps some patients lose 10% or more of their body weight (number needed to treat [NNT] = 10) and appears to be safe in terms of cardiovascular events.


Mar 15, 2019 Issue
Increased Water Intake Decreases UTI Recurrence in Women
Drinking an additional 1.5 liters per day of water halved the recurrence of UTI in women with a history of at least three episodes per year.


Feb 1, 2019 Issue
Clopidogrel Plus Aspirin Provides More Net Benefit Than Aspirin Alone After Minor Stroke or TIA
This study provides support for a strategy of adding clopidogrel to aspirin for the first week or so after a minor ischemic stroke or TIA because this is when the greatest benefit occurs. Harms were spread fairly evenly throughout the study period.


Feb 1, 2019 Issue
Digital Media Use Associated with ADHD Symptom Development Among Adolescents
High school students who reported a high frequency (many times per day) of digital media use (e.g., social networking, streaming movies or music, texting) were significantly more likely to self-report symptoms of ADHD over two years of follow-up (10% higher symptom reporting rate).


Feb 1, 2019 Issue
Chronic Sinusitis: Saline Irrigation Helps Somewhat; Steroid Does Not Add More Benefit
This study showed that patients with chronic rhinosinusitis who continue to use a saline nasal wash (NeilMed) will often experience an improvement in symptoms that can be clinically meaningful, but the addition of the corticosteroid budesonide has yet to show an extra benefit.


Feb 1, 2019 Issue
Decompression Surgery No More Effective Than Exercise for Shoulder Impingement Syndrome
Despite being one of the most common orthopedic surgeries performed, subacromial decompression is not significantly better than physical therapy to treat patients with pain and limited function caused by shoulder impingement.


Jan 1, 2019 Issue
Lower Systolic BP During Antihypertensive Treatment Associated with More Deaths in Older Adults
In this small cohort study of patients older than 85 years, lower systolic blood pressure during treatment with antihypertensive medications is associated with higher death rates and greater cognitive decline.


Jan 1, 2019 Issue
LABA Plus Inhaled Corticosteroid Reduces Exacerbations, But Not Hospitalizations
Adding a LABA to an inhaled corticosteroid is safe but does not reduce the likelihood of a serious exacerbation requiring hospitalization. There is a small reduction in nonsevere asthma exacerbations, with one fewer exacerbation for every 53 patients treated for six months.


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