AFP DEPARTMENT COLLECTION

POEMs: Patient-Oriented Evidence that Matters

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Jan 15, 2021 Issue
Buffering Lidocaine 1%/ Epinephrine with Sodium Bicarbonate in a 3:1 Ratio Is as Effective and Less Painful than a 9:1 Ratio
Lido/Epi buffered with NaHCO3 in a 3:1 ratio is significantly less painful during infiltration than unbuffered Lido/Epi and buffered Lido/Epi in a 9:1 ratio.


Jan 15, 2021 Issue
Triple Inhaled Therapy Provides a Small Reduction in Moderate COPD Exacerbations, No Effect on Severe Exacerbations
Triple inhaled therapy, with budesonide (Pulmicort) in a dose of either 160 mcg or 320 mcg daily plus a long-acting muscarinic antagonist (LAMA) and a long-acting beta2 agonist (LABA), reduces moderate exacerbations (a need for an antibiotic or steroid for three or more days) more than either a LAMA plus a LABA or inhaled corticosteroid plus a LABA, but the difference is small and of questionable clinical significance.


Jan 15, 2021 Issue
Short-Term Low Back Pain Relief with Placebo
Over three weeks, patients with long-term low back pain who knowingly took placebo twice a day reported less pain and disability than those continuing with treatment as usual.


Jan 15, 2021 Issue
Twenty-Year Follow-Up of Women's Health Initiative Trials: Lower Breast Cancer Mortality with Estrogen Alone, No Difference with Estrogen Plus Progesterone
The cumulative 20-year follow-up report from the Women's Health Initiative hormone therapy trials found significantly lower breast cancer incidence and mortality among postmenopausal women who previously took conjugated equine estrogen (CEE; Premarin) alone (with a prior hysterectomy) than in women who took a placebo.


Dec 1, 2020 Issue
Vaginal Bleeding Decreases over Time with a Levonorgestrel Intrauterine System
Bleeding decreased over time for most women after the insertion of a levonorgestrel-releasing intrauterine system.


Dec 1, 2020 Issue
Some Drugs Slightly Improve Cognition in People with Dementia; Effects on Behavioral or Psychological Symptoms Remain Unclear
Some treatments can improve cognition on research scales, but daily function will not be affected in a noticeable way. Managing behavioral or psychological issues with medication is not supported by current evidence


Dec 1, 2020 Issue
Easy Rule Identifies Patients with Low-Risk Penicillin Allergies
A label of penicillin allergy clears the shelves of many effective treatments for various infections. A simple rule outlined in the synopsis effectively identifies (without allergy testing) low-risk penicillin allergies in patients with a history of a penicillin allergy event.


Dec 1, 2020 Issue
Fecal Occult Blood Testing Is Inaccurate as Part of Diagnostic Workup
In this well-conducted systematic review, FOBT, although useful in screening for colorectal cancer, is not highly accurate in evaluating patients with clinical indications.


Nov 15, 2020 Issue
Watch-and-Wait Strategy Is an Option for Primary Spontaneous Pneumothorax
Conservative observation of patients presenting with a first primary spontaneous pneumothorax is as effective as immediate chest tube insertion in achieving full lung re-expansion at eight weeks.


Nov 15, 2020 Issue
Antibiotic and Corticosteroid Treatment Effective for Acute Exacerbations of COPD
Short-term antibiotic treatment and short-term systemic corticosteroids are both associated with a faster resolution of COPD symptoms and fewer treatment failures.


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