AFP DEPARTMENT COLLECTION

POEMs: Patient-Oriented Evidence that Matters

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Jan 1, 2020 Issue
Adding Ultrasonography to Mammography Increases False-Positive Findings Without an Increase in Cancer Detection
Adding ultrasonography to screening mammography in women younger than 50 years at low, intermediate, or high breast cancer risk is not associated with an increase in breast cancer detection. It is associated with increased unnecessary biopsy recommendations and results in more frequent follow-up.


Jan 1, 2020 Issue
Addition of Steroids Improves Outcomes in Children and Adults with CAP
Adding corticosteroid treatment to the management of CAP is beneficial for children and adults. Treatment decreases clinical failures, time in the hospital, and the risk of death in adults with severe pneumonia.


Jan 1, 2020 Issue
Fasting and Nonfasting Lipid Levels Similarly Predict Cardiovascular Disease Risk
Guidelines recommend checking lipid levels in nonfasting patients. They are easier to obtain and are equally predictive of subsequent cardiac events. Although triglyceride levels may be higher in nonfasting patients, cholesterol levels will be similar whether the patient was fasting or not.


Jan 1, 2020 Issue
C-Reactive Protein Guidance Safely Reduces Antibiotic Use in Patients with Acute Exacerbation of COPD
CRP guidance, regarding the likelihood that antibiotics will be helpful for patients with acute exacerbation of COPD, safely reduces antibiotic use (number needed to treat = 5).


Dec 15, 2019 Issue
Platelet-Rich Plasma is Equal to Saline for Patients with Patellar Tendinopathy
In this study, platelet-rich plasma injections were no better than saline injections in improving pain or activity in patients with patellar tendinopathy. It did not matter whether the plasma was leukocyte rich or leukocyte poor.


Dec 15, 2019 Issue
Baloxavir Reduces Symptom Duration Similar to Oseltamivir, Primarily Within 24 Hours of Symptom Onset
Baloxavir has similar efficacy to oseltamivir (Tamiflu) (33-hour reduction in duration of symptoms compared with placebo) and, like oseltamivir, is most effective when given within 24 hours of the onset of symptoms.


Dec 15, 2019 Issue
Augmentation of Antidepressant Treatment Offers Little Benefit
The available evidence that treatment-resistant depression (depression that is unresponsive to two different treatments of adequate dose and length) responds well to augmentation treatment (i.e., adding psychotherapy, lithium, or aripiprazole [Abilify] to current treatment) is weak.


Dec 15, 2019 Issue
One Month of Dual Antiplatelet Therapy Followed by Clopidogrel Alone is Superior to 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention
This study found that one month of dual antiplatelet therapy (aspirin plus clopidogrel or prasugrel [Effient]) followed by clopidogrel monotherapy for up to five years is both noninferior and superior to 12 months of dual antiplatelet therapy followed by aspirin for up to five years for reducing the risk of adverse cardiovascular outcomes and major bleeding complications in adults undergoing successful percutaneous coronary intervention with a drug-eluting stent.


Nov 15, 2019 Issue
Platelet-Rich Plasma Injection Not Beneficial for Nonoperative Treatment of Rotator Cuff Disease
The review found no evidence that supports any additional benefit of platelet-rich plasma injections compared with various control interventions, including saline placebo, in the non-operative treatment of rotator cuff disease in adults.


Nov 15, 2019 Issue
As-Needed Budesonide/Formoterol Similar to Maintenance Budesonide Plus SABA in Patients with Mild Asthma
In these patients with mild asthma (more than one-half used a short-acting beta-agonist [SABA] such as albuterol two or fewer times per week), as-needed use of a combined budesonide/formoterol (Symbicort) inhaler was as effective at preventing exacerbations as daily maintenance budesonide (Pulmicort) plus an as-needed SABA, and both were better than an as-needed SABA alone.


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