Medicine by the Numbers

From The NNT Group (, these provide short, concise, evidence-based ratings of therapies, diagnostic tests, and risk assessments commonly used in family medicine. These rating are based on patient-important benefits and harms.

Jun 1, 2021 Issue
Oxytocin as First-line Uterotonic Therapy for Postpartum Hemorrhage
Oxytocin decreases the chances of a blood transfusion and has fewer adverse effects compared with misoprostol.

May 1, 2021 Issue
Ibuprofen vs. Acetaminophen for Fever or Pain in Children Younger Than Two Years
A meta-analysis found that ibuprofen is more effective than acetaminophen in reducing fever and pain in children younger than two years, although further study is needed to evaluate combination therapy, dosing, and use in children younger than six months.

Apr 1, 2021 Issue
Treatment of Distal DVT
A Cochrane review demonstrated that anticoagulation was effective and superior to observation for deep venous thrombosis; however, given the quality of the evidence, the benefits are unclear.

Mar 1, 2021 Issue
Antiplatelet Agents for Preventing Early Recurrence of Ischemic Stroke or TIA
After atherothrombotic ischemic stroke or transient ischemic attack, adding clopidogrel to aspirin reduced recurrent strokes but increased major hemorrhages.

Feb 15, 2021 Issue
Intravenous Magnesium Sulfate for Acute Asthma Exacerbation in Children and Adults
Patients who received intravenous magnesium sulfate for acute asthma exacerbation in the emergency department had decreased hospital admissions and no serious adverse effects.

Jan 1, 2021 Issue
Effectiveness of Alarm Therapy in the Treatment of Nocturnal Enuresis in Children
This review concluded that alarm therapy appears to be effective for treating nocturnal enuresis in children, but it is uncertain if it is more effective than other interventions.

Dec 1, 2020 Issue
Antibiotics for Uncomplicated Diverticulitis
Learn more about the benefits and harms of antibiotics for uncomplicated diverticulitis.

Nov 1, 2020 Issue
Antibiotics for Acute Bronchitis
Acute bronchitis is a lower respiratory tract infection, most commonly viral, that accounts for a significant number of health care visits. This review discusses the benefits and harms of antibiotics for acute bronchitis or acute productive cough.

Oct 1, 2020 Issue
Antibiotic Prophylaxis for Operative Vaginal Delivery
Current guidelines from the World Health Organization do not recommend routine antibiotic prophylaxis for operative vaginal birth because of insufficient evidence of effectiveness.

Sep 1, 2020 Issue
Aspirin after Acute Ischemic Stroke
Learn more about the effect of aspirin therapy given within 48 hours of acute ischemic stroke in reducing the risk of death, dependence, or recurrent stroke, and the chance of complete recovery.

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