AFP DEPARTMENT COLLECTION
FPIN's Clinical Inquiries
Clinical Inquiries from the Family Physicians Inquiries Network (FPIN) provide short, concise, evidence-based answers to clinical questions common in family medicine. The answers include a summary of the evidence and commentary that puts the answers into perspective.
Jul 01, 2021 Issue
Pharmacologic Management of Agitation in Patients with Dementia
Selective serotonin reuptake inhibitors and risperidone are moderately effective at decreasing agitation in all types of dementia. Olanzapine and risperidone reduce dementia-related agitation much longer than placebo. Dextromethorphan/quinidine may be effective at reducing agitation in patients with dementia.
Jun 1, 2021 Issue
Preoperative A1C Threshold in Patients with Diabetes
In patients with diabetes mellitus who are preparing for total joint replacement, what is the preoperative A1C goal to reduce postoperative periprosthetic joint infections?
May 1, 2021 Issue
Positional Therapies for Obstructive Sleep Apnea
Positional therapies for obstructive sleep apnea produce moderate improvements (16% to 40%) in clinical apnea measures compared with no treatment.
Apr 1, 2021 Issue
Kinesiology Taping for Knee Osteoarthritis Pain
How effective is kinesiology taping (elastic tape applied to the knee to create patellar tension) for osteoarthritis pain of the knee?
Mar 1, 2021 Issue
Platelet-Rich Plasma vs. Corticosteroids for Refractory Plantar Fasciitis
Platelet-rich plasma injections are similar to corticosteroids for pain relief and improvement in function in patients with refractory plantar fasciitis lasting less than 12 weeks.
Feb 1, 2021 Issue
Screening for Cervical Intraepithelial Neoplasia with Patient-Collected HPV Samples
How useful are patient-collected human papillomavirus vaginal swabs as a screening test for cervical intraepithelial neoplasia?
Jan 1, 2021 Issue
Electronic Cigarettes for Smoking Cessation
e-Cigarettes with nicotine can be used to encourage smoking cessation, but continued use after cessation may be a risk factor for relapse.
Dec 1, 2020 Issue
Immunogenicity of Childhood Vaccines after Pediatric Cancer
Children treated for cancer do not retain full immunity from previous vaccinations; therefore, it is likely beneficial for children who survive cancer to be revaccinated six to 12 months after immunosuppressive therapy.
Nov 1, 2020 Issue
Rebound Bilirubin Levels after Phototherapy in Neonates with Hyperbilirubinemia
Rebound elevation of bilirubin levels after phototherapy discontinuation in healthy term neonates is infrequent (fewer than 2% of infants with levels less than 14 mg per dL [239 mmol per L] at initial discontinuation). Obtaining a repeat bilirubin level four to six hours after phototherapy discontinuation is not recommended.
Oct 1, 2020 Issue
Alcohol Use Disorder: Pharmacologic Treatment Options
Acamprosate and naltrexone should be used as first-line agents for treatment of alcohol use disorder and are effective for reducing relapse rates. Agent selection should be based on comorbid conditions and adherence to the dosing regimen.