AFP DEPARTMENT COLLECTION

FPIN's Clinical Inquiries

Clinical Inquiries from the Family Physicians Inquiries Network (FPIN) provide short, concise, evidence-based answers to clinical questions common in family medicine. The answers include a summary of the evidence and commentary that puts the answers into perspective.

Mar 1, 2021 Issue
Platelet-Rich Plasma vs. Corticosteroids for Refractory Plantar Fasciitis
Platelet-rich plasma injections are similar to corticosteroids for pain relief and improvement in function in patients with refractory plantar fasciitis lasting less than 12 weeks.


Feb 1, 2021 Issue
Screening for Cervical Intraepithelial Neoplasia with Patient-Collected HPV Samples
How useful are patient-collected human papillomavirus vaginal swabs as a screening test for cervical intraepithelial neoplasia?


Jan 1, 2021 Issue
Electronic Cigarettes for Smoking Cessation
e-Cigarettes with nicotine can be used to encourage smoking cessation, but continued use after cessation may be a risk factor for relapse.


Dec 1, 2020 Issue
Immunogenicity of Childhood Vaccines after Pediatric Cancer
Children treated for cancer do not retain full immunity from previous vaccinations; therefore, it is likely beneficial for children who survive cancer to be revaccinated six to 12 months after immunosuppressive therapy.


Nov 1, 2020 Issue
Rebound Bilirubin Levels after Phototherapy in Neonates with Hyperbilirubinemia
Rebound elevation of bilirubin levels after phototherapy discontinuation in healthy term neonates is infrequent (fewer than 2% of infants with levels less than 14 mg per dL [239 mmol per L] at initial discontinuation). Obtaining a repeat bilirubin level four to six hours after phototherapy discontinuation is not recommended.


Oct 1, 2020 Issue
Alcohol Use Disorder: Pharmacologic Treatment Options
Acamprosate and naltrexone should be used as first-line agents for treatment of alcohol use disorder and are effective for reducing relapse rates. Agent selection should be based on comorbid conditions and adherence to the dosing regimen.


Sep 1, 2020 Issue
Misoprostol Dosing for First-Trimester Abortion
Vaginal, oral, and sublingual misoprostol in single doses of 600 to 800 mcg are equally effective for promoting completed abortion in patients with an incomplete first-trimester spontaneous abortion.


Aug 1, 2020 Issue
Acupuncture for Knee Osteoarthritis
Electroacupuncture can be used to improve pain and physical function in adults with knee osteoarthritis.


Jul 1, 2020 Issue
Antiemetics for Acute Gastroenteritis in Children
Oral ondansetron (Zofran) may be given to children presenting to the emergency department with vomiting and mild to moderate dehydration from acute gastroenteritis. It reduces hospital admissions and the need for intravenous hydration.


Jun 1, 2020 Issue
Supplemental Oxygen Therapy for Nonhypoxemic Patients with Acute Coronary Syndrome
No conclusive evidence demonstrates that routine use of supplemental oxygen therapy is associated with clinical benefit or harm in nonhypoxemic patients with acute myocardial infarction (MI).


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