AFP DEPARTMENT COLLECTION

Diagnostic Tests: What Physicians Need to Know

The Diagnostic Tests department uses a structured approach to provide concise reviews of new diagnostic tests, including discussions of test accuracy, benefits, harms, cost, and clinical bottom line.

Jan 1, 2020 Issue
PLAC Test for Lp-PLA2 Activity to Predict Coronary Heart Disease
The PLAC test is a blood test used to measure serum activity of lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that breaks down oxidized low-density lipoprotein in the vascular wall.


Nov 1, 2019 Issue
Allopurinol Hypersensitivity Assay HLA-B*58:01 Genotyping
The allopurinol hypersensitivity assay, or HLA-B*58:01 test, is a blood test to detect the presence of a human leukocyte antigen B (HLA-B) genetic variant that increases the risk of life-threatening, severe cutaneous adverse reactions in patients taking allopurinol.


Sep 1, 2019 Issue
Prolaris Test for Prostate Cancer Risk Assessment
The Prolaris test improves the accuracy of prognosis for patients with prostate cancer, especially those with low- or intermediate-grade disease who may be deciding between interventional and noninterventional treatment approaches.


Jul 1, 2019 Issue
mSEPT9 (Epi proColon) Blood Test for Colorectal Cancer Screening
Epi proColon is a blood test used for the detection of the methylated septin 9 (mSEPT9) gene. It is approved by the U.S. Food and Drug Administration for colorectal cancer screening in people at average risk who have declined first-line screening tests.



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