AFP DEPARTMENT COLLECTION

STEPS

This department includes information about new drugs from the perspective of the five attributes to be considered when weighing the advantages of one drug over another: Safety, Tolerability, Effectiveness, Price, and Simplicity.

Jun 15, 2020 Issue
Ozenoxacin (Xepi) for the Treatment of Impetigo
Ozenoxacin is an effective and safe topical quinolone treatment for bullous and nonbullous impetigo in patients as young as two months. However, it is expensive and some patients may have limited access because it is only available through a physician or hospital.


May 15, 2020 Issue
Segesterone Acetate and Ethinyl Estradiol Vaginal Ring (Annovera) for Contraception
Annovera is an effective combined progestin/estrogen contraceptive device that can be used for one year.


Apr 15, 2020 Issue
Galcanezumab (Emgality) for Migraine and Cluster Headaches
In otherwise healthy adults with severe and frequent migraine or cluster headaches, galcanezumab may provide a modest reduction in debilitating headache frequency in the short term.


Mar 15, 2020 Issue
Esketamine (Spravato) for Treatment-Resistant Depression
Esketamine is an in-office treatment for patients with a severe major depressive disorder to be used in addition to oral antidepressant therapy.


Feb 15, 2020 Issue
Dupilumab (Dupixent) for Asthma
Dupilumab is an effective injectable drug that decreases asthma exacerbations and the need for an oral glucocorticoid in patients with moderate to severe asthma, particularly those with high eosinophil counts.


Jan 15, 2020 Issue
Revefenacin (Yupelri) for the Treatment of Chronic Obstructive Pulmonary Disease
Revefenacin is a once-daily nebulized alternative to metered dose long-acting muscarinic antagonists for patients with moderate to severe COPD. Given its expense, complicated administration process, and lack of evidence that it improves key patient-oriented outcomes, its use should be limited to patients who are unable to use a metered dose inhaler.


Dec 15, 2019 Issue
Baloxavir Marboxil (Xofluza) for Influenza
Single-dose baloxavir should be limited to ill patients who cannot tolerate or comply with a course of oseltamivir. For otherwise healthy adults with confirmed influenza or influenza-like illness, the high cost of baloxavir may not justify the one-day reduction in symptoms of a self-limited illness.


Nov 15, 2019 Issue
Hydrogen Peroxide 40% (Eskata) for Seborrheic Keratosis
Hydrogen peroxide 40% topical solution is not particularly effective for removing seborrheic keratosis lesions, and skin reactions are common.


Oct 15, 2019 Issue
Elagolix (Orilissa) for Endometriosis Pain
Elagolix can decrease pain in women with endometriosis, but it is expensive and has adverse effects similar to those of other medications that decrease estrogen levels.


Sep 15, 2019 Issue
Glycopyrronium (Qbrexza) Topical Wipes for Hyperhidrosis
Glycopyrronium wipes are a useful alternative for the topical treatment of hyperhidrosis of the axillae in patients nine years and older who do not respond to or tolerate nonprescription antiperspirants or topical aluminum chloride.


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