Nov 01, 2021 Issue
Tirbanibulin (Klisyri) for the Treatment of Actinic Keratosis [STEPS]

The cost and effectiveness profile of tirbanibulin make it a last-line option compared with current first-line therapies such as fluorouracil and imiquimod, which are less expensive and have a higher clearance rate of AK lesions. Further trials comparing the effectiveness of tirbanibulin and other AK medications are needed.

Jul 01, 2021 Issue
Clascoterone (Winlevi) for the Treatment of Acne [STEPS]

More comparative data are needed to justify the use of clascoterone over less expensive, currently available therapies for moderate to severe acne. However, systemic absorption of clascoterone is low, and it may serve as a safe alternative for patients 12 years and older who saw improvements from or...

Oct 15, 2020 Issue
Trifarotene (Aklief) for the Treatment of Acne [STEPS]

Trifarotene is a monotherapy option for acne affecting the face and trunk and offers an alternative to topical antibiotics or anti-inflammatory agents for the management of moderate inflammatory and noninflammatory acne.

Aug 15, 2020 Issue
Sarecycline (Seysara) for the Treatment of Acne [STEPS]

Sarecycline is a once-daily oral medication for patients with moderate to severe non-nodular acne. Its benefit over less expensive options has not been demonstrated.

Oct 15, 2019 Issue
Acne Vulgaris: Diagnosis and Treatment [Article]

Treatment of acne is based on severity and usually includes topical agents such as retinoids, benzoyl peroxide, and antibiotics. Oral antibiotics and isotretinoin may be used for severe, recalcitrant acne. Combination oral contraceptives and spironolactone are also used in some patients. Further study is needed to determine the effectiveness of complementary therapies and physical modalities such as laser therapy and light therapy.

Jun 1, 2017 Issue
Acne Vulgaris: Treatment Guidelines from the AAD [Practice Guidelines]

Acne vulgaris, which occurs in 50 million persons living in the United States, is associated with physical and psychological morbidity (e.g., scarring, poor self-image, depression) and results in more than $3 billion in direct costs annually. In addition, knowledge about its pathogenesis is constant...

Jan 15, 2017 Issue
Chocolate Consumption May Make Acne Vulgaris Worse [POEMs]

This study found a statistically significant increase in facial acne lesions among college students 48 hours after ingesting chocolate instead of jelly beans (average compared with baseline: 4.8 new lesions vs. 0.7 fewer lesions, respectively).

Sep 1, 2016 Issue
Family Physicians Are Well Suited to Prescribe Isotretinoin [Editorials]

A few minutes (and a few clicks on the computer) can open up rewarding therapeutic opportunities when registering with iPledge to prescribe isotretinoin.

Apr 1, 2015 Issue
Exophytic Growths on the Back [Photo Quiz]

A man with a history of significant acne presented with exophytic growths on his back and extensive scarring on his chest.

Sep 1, 2013 Issue
Minocycline for Acne Vulgaris [Cochrane for Clinicians]

Compared with placebo, minocycline generally improves acne, but it offers no clinical advantages over other therapies and has more serious adverse effects.

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