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Trifarotene is a monotherapy option for acne affecting the face and trunk and offers an alternative to topical antibiotics or anti-inflammatory agents for the management of moderate inflammatory and noninflammatory acne.
Sarecycline is a once-daily oral medication for patients with moderate to severe non-nodular acne. Its benefit over less expensive options has not been demonstrated.
Treatment of acne is based on severity and usually includes topical agents such as retinoids, benzoyl peroxide, and antibiotics. Oral antibiotics and isotretinoin may be used for severe, recalcitrant acne. Combination oral contraceptives and spironolactone are also used in some patients. Further study is needed to determine the effectiveness of complementary therapies and physical modalities such as laser therapy and light therapy.
Acne vulgaris, which occurs in 50 million persons living in the United States, is associated with physical and psychological morbidity (e.g., scarring, poor self-image, depression) and results in more than $3 billion in direct costs annually. In addition, knowledge about its pathogenesis is constant...
This study found a statistically significant increase in facial acne lesions among college students 48 hours after ingesting chocolate instead of jelly beans (average compared with baseline: 4.8 new lesions vs. 0.7 fewer lesions, respectively).
A few minutes (and a few clicks on the computer) can open up rewarding therapeutic opportunities when registering with iPledge to prescribe isotretinoin.
A man with a history of significant acne presented with exophytic growths on his back and extensive scarring on his chest.
Compared with placebo, minocycline generally improves acne, but it offers no clinical advantages over other therapies and has more serious adverse effects.
Acne is a chronic inflammatory skin disease that is the most common skin disorder in the United States. Therapy targets the four factors responsible for lesion formation: increased sebum production, hyperkeratinization, colonization by Propionibacterium acnes, and the resultant inflammatory reaction...
Adapalene/benzoyl peroxide is as effective as other combination products for the treatment of acne. Once-daily application is an advantage in terms of simplicity and adherence to therapy, but the cost is much higher than that of the individual components sold separately; this may create a barrier to adherence.