Allergy and Anaphylaxis

Jan 01, 2022 Issue
Pruritus: Diagnosis and Management [Article]

Pruritus is the sensation of itching; it can be caused by dermatologic and systemic conditions. An exposure history may reveal symptom triggers. A thorough skin examination, including visualization of the finger webs, anogenital region, nails, and scalp, is essential. Primary skin lesions indicate d...

Jan 01, 2022 Issue
Peanut Allergen Powder (Palforzia) for Peanut Allergy [STEPS]

For individuals with severe peanut allergy, peanut allergen powder may lessen the likelihood of life-threatening consequences of accidental ingestion of small amounts of peanuts. Patients must still adhere to a peanut-avoidant diet, which likely has far bigger preventive impact than peanut allergen powder therapy.

Jun 15, 2021 Issue
Predicting True Penicillin Allergy in Adults [Point-of-Care Guides]

In patients reporting a penicillin allergy, is it possible to determine the likelihood of true allergy without formal testing?

May 1, 2021 Issue
Eosinophilic Esophagitis: Management Guidelines from the AGA and JTF [Practice Guidelines]

The American Gastroenterological Association (AGA) and the Joint Task Force on Allergy-Immunology Practice Parameters (JTF) published guidelines for treatment of eosinophilic esophagitis.

Dec 1, 2020 Issue
Easy Rule Identifies Patients with Low-Risk Penicillin Allergies [POEMs]

A label of penicillin allergy clears the shelves of many effective treatments for various infections. A simple rule outlined in the synopsis effectively identifies (without allergy testing) low-risk penicillin allergies in patients with a history of a penicillin allergy event.

Sep 15, 2020 Issue
Anaphylaxis: Recognition and Management [Article]

The incidence of anaphylaxis in the United States is 2.1 per 1,000 person-years. Common symptoms of anaphylaxis are urticaria, difficulty breathing, and mucosal swelling, and most anaphylactic reactions occur outside the hospital setting. Acute management of anaphylaxis involves removal of the trigger; early administration of intramuscular epinephrine; supportive care for the patient’s airway, breathing, and circulation; and a period of observation for potential biphasic reactions.

Jul 15, 2020 Issue
No Cow's Milk Formula for the First Three Days of Life Prevents Food Allergies [POEMs]

In infants at increased risk of atopy, restricting cow's milk supplementation for the first three days of life is associated with a significantly lower risk of developing a cow's milk allergy or food allergies by 24 months of age.

May 15, 2020 Issue
Atopic Dermatitis: Diagnosis and Treatment [Article]

Atopic dermatitis is a chronic relapsing and remitting inflammatory skin disease that causes intensely pruritic skin lesions. Maintenance therapy consists of liberal use of emollients and daily bathing with soap-free cleansers. Use of topical corticosteroids is the first-line treatment for flare-ups, with or without the addition of a calcineurin inhibitor. Ultraviolet phototherapy is a safe and effective second-line treatment for moderate to severe atopic dermatitis.

Jul 15, 2019 Issue
Ankle Sprains, Counseling Strategies, Dysphonia, Acute Coronary Syndrome, Egg Allergy [AFP Clinical Answers]

Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

Feb 1, 2019 Issue
Oral Immunotherapy for Egg Allergy [Cochrane for Clinicians]

Providing daily, steadily increasing doses of egg protein over an extended period of time effectively diminishes the immunoglobulin E (IgE)-mediated allergic response among children with egg allergy.

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