Oct 1, 2005 Issue
Diagnosis and Management of G6PD Deficiency [Article]

Glucose-6-phosphate dehydrogenase deficiency, the most common enzyme deficiency worldwide, causes a spectrum of disease including neonatal hyperbilirubinemia, acute hemolysis, and chronic hemolysis. Persons with this condition also may be asymptomatic. This X-linked inherited disorder most commonly ...

Jun 1, 2004 Issue
Hemolytic Anemia [Article]

Hemolysis presents as acute or chronic anemia, reticulocytosis, or jaundice. The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings. Premature destruction of erythrocytes occurs intravasc...

Mar 1, 2003 Issue
Vitamin B12 Deficiency [Article]

Vitamin B12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been implicated in a spectrum of neuropsychiatric disorders. The role of B12 deficiency in hyperhomocysteinemia and the promotion of atherosclerosis is only now being explored. Diagnosis of vitamin B12 deficiency is ty...

Oct 1, 2002 Issue
Prevention of Iron Deficiency in Infants and Toddlers [Article]

The prevalence of nutritional iron deficiency anemia in infants and toddlers has declined dramatically since 1960. However, satisfaction with this achievement must be tempered because iron deficiency anemia in infants and toddlers is associated with long-lasting diminished mental, motor, and behavio...

Oct 15, 2001 Issue
Anemia in Children [Article]

Anemia in children is commonly encountered by the family physician. Multiple causes exist, but with a thorough history, a physical examination and limited laboratory evaluation a specific diagnosis can usually be established. The use of the mean corpuscular volume to classify the anemia as microcyti...

Nov 15, 2000 Issue
Normocytic Anemia [Article]

Anemia is a common problem that is often discovered on routine laboratory tests. Its prevalence increases with age, reaching 44 percent in men older than 85 years. Normocytic anemia is the most frequently encountered type of anemia. Anemia of chronic disease, the most common normocytic anemia, is fo...

Oct 1, 2000 Issue
Anemia in the Elderly [Article]

Anemia should not be accepted as an inevitable consequence of aging. A cause is found in approximately 80 percent of elderly patients. The most common causes of anemia in the elderly are chronic disease and iron deficiency. Vitamin B12 deficiency, folate deficiency, gastrointestinal bleeding and mye...

Aug 1, 2000 Issue
Screening for Iron Deficiency Anemia Among Children and Adolescents [Putting Prevention into Practice]

Case study: Reflecting on your last office session, you recall several pediatric visits. Among these was a visit from a six-month-old infant who was brought in for a checkup and completion of papers for the Women, Infants and Children (WIC) program. You ordered blood work for this infant, because it was required by the program.

Mar 15, 1999 Issue
Ambulatory Management of Common Forms of Anemia [Article]

Anemia is a prevalent condition with a variety of underlying causes. Once the etiology has been established, many forms of anemia can be easily managed by the family physician. Iron deficiency, the most common form of anemia, may be treated orally or, rarely, parenterally. Vitamin B12 deficiency has...

Feb 15, 1999 Issue
'Common' Uncommon Anemias [Article]

Of the uncommon anemias, "common" types include the anemia of renal disease, thalassemia, myelodysplastic syndrome and the anemia of chronic disease. These conditions may be suggested by the clinical presentation, laboratory test values and peripheral blood smear, or by failure of the anemia to resp...

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