Arthritis and Joint Pain

Oct 1, 2019 Issue
Oral Antibiotics Are Equal to IV Antibiotics for Serous Bone and Joint Infections [POEMs]

Oral antibiotics started within seven days of surgery for patients with a serious bone or joint infection are as safe and effective as six weeks of IV antibiotics.

Jun 1, 2018 Issue
Ultrasound Is Reasonably Accurate in Detecting Synovitis in Patients with Rheumatoid Arthritis [POEMs]

In this systematic review of patients with rheumatoid arthritis, ultrasonography was reasonably accurate compared with magnetic resonance imaging (MRI) in detecting synovitis in fingers and wrists. The use of MRI as a reference standard is convenient, but problematic.

May 1, 2018 Issue
Effectiveness and Safety of Celecoxib for the Treatment of Rheumatoid Arthritis [Cochrane for Clinicians]

Compared with placebo, celecoxib improves pain (number needed to treat [NNT] = 4) and clinical symptoms (NNT = 7), but it has no effect on physical function in patients with RA.

Apr 1, 2018 Issue
Rheumatoid Arthritis: Common Questions About Diagnosis and Management [Article]

Early diagnosis and treatment of rheumatoid arthritis are associated with better outcomes for patients. Methotrexate is the disease-modifying antirheumatic drug of choice, although other nonbiologic and biologic agents are available. Patients should be screened for chronic infections before beginning treatment for rheumatoid arthritis.

Nov 15, 2017 Issue
Spondyloarthritis: NICE Releases Guidelines on Diagnosis and Treatment [Practice Guidelines]

Spondyloarthritis comprises inflammatory disorders that have some overlapping characteristics. The National Institute for Health and Care Excellence (NICE) released a guideline on diagnosing and treating spondyloarthritis.

Nov 15, 2016 Issue
Acute Monoarthritis: Diagnosis in Adults [Article]

Osteoarthritis, gout, and trauma are the most common causes of acute monoarthritis. Review the typical history and examination findings for these and other etiologies. If infection is suspected, arthrocentesis should be performed for synovial fluid analysis.

Jul 1, 2015 Issue
Differential Diagnosis of Polyarticular Arthritis [Article]

Many conditions can cause joint pain. Diagnosis requires distinguishing between inflammatory and noninflammatory arthritis, as well as recognizing nonarticular conditions. Learn the common symptoms and signs of the possible etiologies of joint pain.

May 15, 2015 Issue
Acute Onset of Polyarthralgia and Skin Plaques [Photo Quiz]

A man presented with severe pain and swelling in his knees and wrists that affected his ability to walk, and a rash on his thighs, knees, hands, and lower back.

Jan 1, 2015 Issue
Methotrexate Therapy for Rheumatoid Arthritis [Cochrane for Clinicians]

Methotrexate monotherapy demonstrated statistically significant and clinically relevant improvement of symptoms and physical function compared with placebo at 12 to 52 weeks. Multiple adverse effects were reported with methotrexate use, and patients were twice as likely to discontinue methotrexate therapy when compared with placebo.

Dec 15, 2014 Issue
Diagnosis, Treatment, and Prevention of Gout [Article]

Find out whether newer medications are any more effective than older ones, and the latest evidence on dietary modifications and pharmacologic therapy for prevention of recurrent gout.

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