Arthritis and Joint Pain

Apr 1, 2014 Issue
Platelet-Rich Plasma May Minimally, If at All, Benefit Patients with Knee Osteoarthritis [POEMs]

Compared with normal saline or hyaluronic acid, multiple intra-articular injections of platelet-rich plasma significantly improved knee function but did not reduce perceived pain or improve patient satisfaction in adults with symptomatic knee osteoarthritis.

Oct 15, 2013 Issue
Surgery Plus PT Similar to PT Alone for Adults with Meniscal Tear and Osteoarthritis [POEMs]

For middle-aged or older adults with osteoarthritis and a meniscal tear, there seem to be no significant differences between arthroscopic surgery plus PT and PT alone. A subset of patients who do not respond well to PT alone will eventually have surgery, but if they cross over to surgery within six ...

Sep 1, 2013 Issue
Vitamin D Does Not Reduce Knee Pain from Osteoarthritis [POEMs]

Vitamin D supplementation at a dose targeted to reach a 25-hydroxyvitamin D plasma level greater than 36 ng per mL for two years did not reduce symptomatic knee pain in adults with osteoarthritis.

Feb 1, 2013 Issue
Hyaluronic Acid Ineffective for Knee Osteoarthritis [POEMs]

Hyaluronic acid injection does not improve pain in patients with knee osteoarthritis but may result in serious adverse effects.

Jan 1, 2012 Issue
Osteoarthritis: Diagnosis and Treatment [Article]

Osteoarthritis is a common degenerative disorder of the articular cartilage associated with hypertrophic bone changes. Risk factors include genetics, female sex, past trauma, advancing age, and obesity. The diagnosis is based on a history of joint pain worsened by movement, which can lead to disabil...

Dec 1, 2011 Issue
Diagnosis and Management of Rheumatoid Arthritis [Article]

Rheumatoid arthritis is the most commonly diagnosed systemic inflammatory arthritis. Women, smokers, and those with a family history of the disease are most often affected. Criteria for diagnosis include having at least one joint with definite swelling that is not explained by another disease. The l...

Sep 15, 2011 Issue
Approach to Septic Arthritis [Article]

Prompt diagnosis and treatment of infectious arthritis can help prevent significant morbidity and mortality. The acute onset of monoarticular joint pain, erythema, heat, and immobility should raise suspicion of sepsis. Constitutional symptoms such as fever, chills, and rigors are poorly sensitive fo...

Sep 1, 2011 Issue
Exercise for the Treatment of Knee Osteoarthritis [FPIN's Clinical Inquiries]

Regular exercise reduces osteoarthritic knee pain and improves functioning.

Jun 1, 2011 Issue
Treatment of Knee Osteoarthritis [Article]

Knee osteoarthritis is a common disabling condition that affects more than one-third of persons older than 65 years. Exercise, weight loss, physical therapy, intra-articular corticosteroid injections, and the use of nonsteroidal anti-inflammatory drugs and braces or heel wedges decrease pain and imp...

Dec 15, 2008 Issue
Adalimumab (Humira) for the Treatment of Rheumatoid Arthritis [STEPS]

Adalimumab used alone offers little benefit over the traditional first-line agent, methotrexate. However, it increases remission rates when combined with methotrexate in early aggressive rheumatoid arthritis and when combined with traditional DMARDs in those who have not derived benefit from existin...

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