Cancer Care

Feb 1, 2021 Issue
Targeted Cancer Therapies [Article]

Targeted cancer therapies are chemotherapeutic agents that directly or indirectly attack a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. Targeted oncology has improved survival by years for some incurable cancers; however, as few as 8% of patients with advanced cancer qualify for targeted drugs, and even fewer benefit. Other limitations include possible serious adverse effects. Immune related–adverse effects are common with immunotherapy, and more severe events can be fatal and require immediate intervention. Financial toxicities are an emerging problem for patients with cancer who are taking costly targeted therapies. Future directions for targeted oncology include tumor-agnostic drugs.

Jan 1, 2015 Issue
Surveillance of the Adult Cancer Survivor [Article]

As the number of cancer survivors grows, family physicians continue to play a vital role in providing health maintenance and preventive services, and managing complications and comorbidities.

May 15, 2010 Issue
Primary Care of Adult Survivors of Childhood Cancer [Article]

There are approximately 300,000 survivors of childhood cancer in the United States, and most of them receive their medical care from primary care physicians. Adult survivors of childhood cancer are at considerable risk of long-term morbidity and mortality beyond the recurrence of their primary ma...

Dec 1, 2008 Issue
Recent Advances in Radiation Therapy [Article]

Recent advances have improved the effectiveness, decreased the complications, and expanded the implications of radiation therapy. These advances include three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, stereotactic radiotherapy, brachytherapy, and radioimmunother...

Jun 1, 2008 Issue
Lifestyle Interventions to Reduce Cancer Risk and Improve Outcomes [Article]

There are more than one half million cancer deaths in the United States each year, and one third of these deaths are attributed to suboptimal diet and physical activity practices. Maintaining a healthy weight, staying physically active throughout life, and consuming a healthy diet can substantially ...

Feb 1, 2008 Issue
Targeted Therapies: A New Generation of Cancer Treatments [Article]

Targeted therapies, which include monoclonal antibodies and small molecule inhibitors, have significantly changed the treatment of cancer over the past 10 years. These drugs are now a component of therapy for many common malignancies, including breast, colorectal, lung, and pancreatic cancers, as we...

Apr 15, 2007 Issue
Primary Care of the Patient with Cancer [Article]

Care of patients with cancer can be enhanced by continued involvement of the primary care physician. The physician's role may include informing the patient of the diagnosis, helping with decisions about treatment, providing psychological support, treating intercurrent disease, continuing patient-app...

Aug 1, 2005 Issue
NSAIDs Alone or with Opioids as Therapy for Cancer Pain [Cochrane for Clinicians]

Short-term trials indicate that cancer pain can be reduced with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) as initial monotherapy. NSAIDs combined with opioids can result in slight short-term improvement in pain compared with either agent alone. Long-term efficacy and safety of NSAIDs for cancer pain have not been established.

Feb 15, 2005 Issue
Care of Cancer Survivors [Article]

Cancer survivors are at increased risk for recurrence of their original malignancy; development of second primary malignancies; and medical, developmental, and psychologic problems resulting from cancer therapy, genetic predisposition to cancer, and other risk factors. Surveillance following curativ...

Apr 1, 2004 Issue
ACS Releases Guidelines on Nutrition and Physical Activity During and After Cancer Treatment [Practice Guidelines]

The American Cancer Society (ACS) issued a report discussing optimal nutrition and physical activity issues during the phases of cancer treatment and recovery, living after recovery from treatment, and living with advanced cancer.

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