Celiac Disease

Mar 1, 2019 Issue
Gas, Bloating, and Belching: Approach to Evaluation and Management [Article]

Gas, bloating, and belching are primarily caused by functional gastrointestinal disorders; psychological distress can make symptoms worse. Exhaustive testing is not necessary for diagnosis. Most patients are classified as having gastric or small bowel bloating, bloating with constipation, or belching disorders. Patients with symptoms of irritable bowel syndrome should be tested for celiac disease; patients with chronic constipation should have a rectal examination. There is insufficient evidence to support the routine use of highly restrictive exclusion diets except in patients with confirmed celiac disease.

Sep 15, 2017 Issue
Screening for Celiac Disease: Recommendation Statement [U.S. Preventive Services Task Force]

The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for celiac disease in asymptomatic persons.

Jun 1, 2017 Issue
Comparative Accuracy of Diagnostic Tests for Celiac Disease [Implementing AHRQ Effective Health Care Reviews]

What is the best test for celiac disease in terms of sensitivity, specificity, and safety?

May 1, 2016 Issue
Gluten Is Not the Culprit in Many Patients’ Symptoms [POEMs]

Gluten may not be the cause of gastrointestinal symptoms in many patients with nonceliac gluten sensitivity. Only one-third of patients on a gluten-free diet experienced symptoms and correctly identified when they were given gluten-containing flour. Almost one-half (49%) of patients experienced symp...

Mar 15, 2015 Issue
Mixed Benefits of Gluten-Free Diet in Asymptomatic Patients with Celiac Disease [POEMs]

Screening of asymptomatic relatives of patients with known celiac disease identified approximately 5% who were antibody-positive. Compared with their normal diet, a gluten-free diet improved some yet unrecognized symptoms but seemed to interfere with normal social activities in these patients.

Mar 15, 2014 Issue
ACG Releases Guideline on Diagnosis and Management of Celiac Disease [Practice Guidelines]

There has been a substantial increase in the prevalence of celiac disease over the past 50 years, and in the rate of diagnosis over the past decade. Despite this, it remains underdiagnosed in the United States. The American College of Gastroenterology (ACG) has released clinical guidelines with reco...

Jan 15, 2014 Issue
Celiac Disease: Diagnosis and Management [Article]

Celiac disease is an autoimmune disorder of the gastrointestinal tract. It is triggered by exposure to dietary gluten in genetically susceptible individuals. Gluten is a storage protein in wheat, rye, and barley, which are staples in many American diets. Celiac disease is characterized by chronic in...

Dec 15, 2007 Issue
Celiac Disease [Article]

Patients with persistent gastrointestinal symptoms such as diarrhea, abdominal pain, and bloating should be evaluated for celiac disease. Immunoglobulin A tissue transglutaminase antibody testing is recommended, with confirmatory small bowel biopsy in most patients. Adherence to a gluten-free diet may eliminate symptoms within a few months

May 1, 2005 Issue
AHRQ Releases Practice Guidelines for Celiac Disease Screening [Practice Guidelines]

The Agency for Healthcare Research and Quality has issued a systematic review of the evidence regarding screening patients for celiac disease. Celiac disease is also referred to as celiac sprue, gluten-sensitive enteropathy, and non-tropical sprue.

Jan 15, 2005 Issue
Diagnosis of Celiac Disease [Practice Guidelines]

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