ITEMS IN AFP WITH KEYWORD:
With more than 200 types identified, human papillomavirus (HPV) commonly causes infections of the skin and mucosa. HPV infection is the most common sexually transmitted infection in the United States. Although most HPV infections are transient and subclinical, some lead to clinical manifestations ra...
HPV vaccination is associated with a significant reduction in the likelihood of invasive cervical cancer.
Changes in cervical cancer screening and guidelines, human papillomavirus (HPV) vaccination recommendations, and colposcopy standards from the American Society for Colposcopy and Cervical Pathology have implications for all primary care clinicians. Cervical cancer prevention (with HPV vaccination), risk reduction (with smoking cessation counseling and support), screening, detection of precancerous cervical lesions, treatment, and post-treatment follow-up all can be performed by primary care clinicians.
Sep 15, 2019 Issue
Cervical Cancer, Febrile Seizures, HIV Infection, Dyspepsia [AFP Clinical Answers]
Key clinical questions and their evidence-based answers directly from the journal's content, written by and for family physicians.
Apr 1, 2019 Issue
HPV Vaccine for Prevention of High-Grade Precancerous Cervical Lesions [Medicine by the Numbers]
Data suggest the benefits of HPV vaccination for reducing precancerous lesions outweigh the potential harms. Find out more.
Feb 15, 2019 Issue
Screening for Cervical Cancer: Recommendation Statement [U.S. Preventive Services Task Force]
The USPSTF recommends screening for cervical cancer every 3 years with cervical cytology alone in women aged 21 to 29 years. For women aged 30 to 65 years, the USPSTF recommends screening every 3 years with cervical cytology alone, every 5 years with high-risk human papillomavirus (hrHPV) testing al...
P.J., a 48-year-old woman, presents to your office for a well-woman examination. She has been married for eight years, has no history of sexually transmitted diseases, and has nothing remarkable in her medical history.
HPV vaccination in women 15 to 26 years of age prevents the development of cervical intraepithelial neoplasia (CIN) 2 and CIN 3 in women regardless of previous HPV exposure (number needed to treat [NNT] = 39). No serious adverse effects are associated with administration of the HPV vaccine.
In women who had received the HPV vaccine, screening for HPV every five years, with cytology and colposcopy follow-up as needed, resulted in higher rates of identification of high-grade pre-cancerous disease than standard liquid-based cytology every 2.5 years with HPV follow-up cotesting as needed.
Cervical cancer may be detected after a Papanicolaou test result is abnormal, a lesion is visualized on pelvic examination, or clinical symptoms develop. Once cervical cancer is diagnosed, treatment may involve surgery, radiation therapy, chemotherapy, or a combination. The choice of therapy depends on the stage of disease, lymph node involvement, patient comorbidities, and risk factors for recurrence.