Cervical Cancer

Sep 15, 2018 Issue
HPV Testing Better Than Cytology for Women Vaccinated Against HPV [POEMs]

In women who had received the HPV vaccine, screening for HPV every five years, with cytology and colposcopy follow-up as needed, resulted in higher rates of identification of high-grade pre-cancerous disease than standard liquid-based cytology every 2.5 years with HPV follow-up cotesting as needed.

Apr 1, 2018 Issue
Cervical Cancer: Evaluation and Management [Article]

Cervical cancer may be detected after a Papanicolaou test result is abnormal, a lesion is visualized on pelvic examination, or clinical symptoms develop. Once cervical cancer is diagnosed, treatment may involve surgery, radiation therapy, chemotherapy, or a combination. The choice of therapy depends on the stage of disease, lymph node involvement, patient comorbidities, and risk factors for recurrence.

Apr 1, 2018 Issue
Cervical Cancer Screening [Article]

Cervical cancer screening methods include cytology and human papillomavirus (HPV) testing. Although primary HPV testing is now considered an option, most major guidelines still recommend cytology alone or cotesting with cytology plus HPV testing. Learn which patients may benefit from screening and how to choose a screening method.

Apr 1, 2017 Issue
Repeat Cytology Within Six Months Equals Colposcopy for Younger Women with ASCUS or LSIL [POEMs]

Among women 22 to 27 years of age with an index cervical cytology showing abnormal squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL), the incidence of invasive cervical cancer did not differ between repeat cytology within six months or colposcopy with biopsy within six months.

Dec 1, 2016 Issue
Cervical Treatment Associated with Adverse Obstetric Outcomes [POEMs]

Cervical treatments for dysplasia and early cervical carcinoma are associated with subsequent risk of preterm birth. Excisional treatments carry higher risk than ablative treatments, and multiple treatments carry higher risk than single treatments. The frequency and severity of prematurity-related o...

Dec 15, 2015 Issue
ACP Releases Best Practice Advice on Screening for Cervical Cancer [Practice Guidelines]

Based on the best available evidence, the American College of Physicians (ACP) has released best practice advice on cervical cancer screening in average-risk, asymptomatic women 21 years or older. This advice is targeted to all clinicians, and refers to screening for cervical precancerous and cancer...

Apr 1, 2015 Issue
CIN Treatment May Increase Miscarriages but Does Not Affect Fertility [POEMs]

In this analysis of 15 observational studies (it would be difficult and unethical to do randomized research on this topic), excision using any method for CIN did not affect fertility, although second trimester miscarriages were more likely. A study published at the same time found the risk of preter...

Dec 1, 2013 Issue
ACOG Releases Guidelines on Cervical Cancer Screening [Practice Guidelines]

The incidence of cervical cancer, as well as mortality rates from the disease, has decreased over the past 30 years because of widespread screening with cervical cytology. Screening technologies and risk-benefit considerations for different age groups continue to evolve. The American College of Obst...

Jun 15, 2013 Issue
Gynecologic Procedures: Colposcopy, Treatments of Cervical Intraepithelial Neoplasia, and Endometrial Assessment [Article]

Women who have abnormal Papanicolaou test results may undergo colposcopy to determine the biopsy site for histologic evaluation. Traditional grading systems do not accurately assess lesion severity because colposcopic impression alone is unreliable for diagnosis. The likelihood of finding cervical i...

Sep 15, 2012 Issue
Screening for Cervical Cancer: Recommendation Statement [U.S. Preventive Services Task Force]

The U.S. Preventive Services Task Force (USPSTF) recommends screening for cervical cancer in women 21 to 65 years of age with cytology (Papanicolaou [Pap] smear) every three years or, for women 30 to 65 years of age who want to lengthen the screening interval, screening with a combination of cytolog...

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