Chronic Obstructive Pulmonary Disease

Jun 1, 2015 Issue
Aclidinium for Stable COPD [Cochrane for Clinicians]

Aclidinium did not decrease all-cause mortality or exacerbations requiring oral steroids, antibiotics, or both. However, aclidinium decreased the number of patients with exacerbations requiring hospitalization and improved quality of life in those with stable COPD.

Aug 15, 2014 Issue
Indacaterol (Arcapta) for COPD [STEPS]

Indacaterol provides a similar benefit to other long-acting bronchodilators for the treatment of moderate to severe COPD, with once-daily dosing. As with other LABAs, it should be used only as add-on therapy in patients already taking inhaled corticosteroids.

Jun 1, 2014 Issue
Prophylactic Antibiotics for the Prevention of COPD Exacerbation [Cochrane for Clinicians]

Continuous prophylactic antibiotic therapy significantly decreases COPD exacerbations for up to three years. However, it does not decrease mortality, and it puts the patient at risk of antibiotic-resistant colonization and infection.

Feb 15, 2014 Issue
Roflumilast (Daliresp) for Chronic Obstructive Pulmonary Disease [STEPS]

Roflumilast therapy has a limited role in patients with severe COPD, and no role in patients with mild to moderate COPD. It will not decrease the number of hospitalizations.

Jan 1, 2014 Issue
Role of Breathing Exercises in the Treatment of COPD [Cochrane for Clinicians]

Patients with COPD who are treated with breathing exercises vs. standard care showed an improvement in exercise capacity, with inconsistent changes in dyspnea and health-related quality of life. Adding breathing exercises to a pulmonary rehabilitation program did not show any increased benefit. Brea...

Dec 1, 2013 Issue
Five-Day Steroid Treatment Effective for Acute COPD Exacerbation [POEMs]

A five-day course of systemic glucocorticoids is at least as effective as a 14-day course in the treatment of adults with acute exacerbations of COPD.

Nov 15, 2013 Issue
Choosing the Right Inhaled Medication Device for COPD [Editorials]

Data suggest that inhaler devices have similar effectiveness in treating patients with COPD; however, a variety of factors must be considered when selecting the best device for each patient.

Nov 15, 2013 Issue
Treatment of Stable Chronic Obstructive Pulmonary Disease: the GOLD Guidelines [Article]

Chronic obstructive pulmonary disease (COPD) is a common problem in primary care. COPD is diagnosed with spirometry only in clinically stable patients with a postbronchodilator forced expiratory volume in one second/forced vital capacity ratio of less than 0.70. All patients with COPD who smoke shou...

Apr 1, 2013 Issue
Amoxicillin/Clavulanate During COPD Exacerbations Decreases Symptoms and Delays Subsequent Exacerbations [POEMs]

Patients with exacerbations of mild to moderate COPD have a higher rate of cure when given amoxicillin/clavulanate compared with placebo.

Jan 15, 2012 Issue
ACP Updates Guideline on Diagnosis and Management of Stable COPD [Practice Guidelines]

Chronic obstructive pulmonary disease (COPD) affects more than 5 percent of U.S adults and is the third leading cause of death. The American College of Physicians (ACP) recently updated its 2007 guideline on the diagnosis and management of stable COPD to include new recommendations on when to consid...

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