Chronic Obstructive Pulmonary Disease

Sep 1, 2004 Issue
Home Oxygen Therapy for Treatment of Patients with Chronic Obstructive Pulmonary Disease [Cochrane for Clinicians]

There is good evidence that the addition of home long-term continuous oxygen therapy for COPD increases survival rates in patients with severe hypoxemia (i.e., O2 saturation of less than 90 percent or partial pressure of arterial oxygen [PaO2] of less than 8 kPa per 60 mm Hg) but not in patients with moderate hypoxemia or nocturnal desaturation.

Jun 15, 2004 Issue
Tiotropium (Spiriva) for COPD [STEPS]

Tiotropium improves dyspnea, decreases COPD exacerbations and hospitalizations, decreases albuterol use, improves health-related quality of life and increases mean trough FEV1. Tiotropium was more effective than ipratropium and salmeterol in improving TDI scores. It was more effective than ipratropi...

Sep 1, 2002 Issue
Chronic Obstructive Pulmonary Disease [Clinical Evidence Handbook]

What are the short- and long-term effects of maintenance drug treatment?

Aug 15, 2001 Issue
COPD: Management of Acute Exacerbations and Chronic Stable Disease [Article]

Acute exacerbations of chronic obstructive pulmonary disease (COPD) are treated with oxygen (in hypoxemic patients), inhaled beta2 agonists, inhaled anticholinergics, antibiotics and systemic corticosteroids. Methylxanthine therapy may be considered in patients who do not respond to other bronchodil...

May 15, 1998 Issue
Chronic Bronchitis: Primary Care Management [Article]

Chronic bronchitis is a clinical diagnosis characterized by a cough productive of sputum for over three months' duration during two consecutive years and the presence of airflow obstruction. Pulmonary function testing aids in the diagnosis of chronic bronchitis by documenting the extent of reversibi...

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