Colorectal Cancer

Aug 15, 2014 Issue
Immunochemical FOBTs Moderately Sensitive and Highly Specific for Colorectal Cancer [POEMs]

Immunochemical FOBTs, such as OC-Micro, OC-Sensor, or OC-Light, are moderately sensitive (73% to 89%) and highly specific (92% to 95%) for identifying colorectal cancer. In comparison, Hemoccult Sensa has a lower sensitivity (64% to 80%) and specificity (87% to 90%). Immunochemical FOBTs also have the advantage of requiring only one sample.

May 1, 2014 Issue
No Increased Survival Benefit to Intensive Follow-Up After Colorectal Cancer Surgery [POEMs]

Compared with minimal follow-up after surgery for colorectal cancer, intensive follow-up with regular computed tomography (CT), carcinoembryonic antigen (CEA) testing, or both results in more patients undergoing repeat surgery but no reduction in overall mortality or disease-specific mortality.

Oct 15, 2013 Issue
Colorectal Neoplasia Yield Similar for FIT Every One, Two, or Three Years [POEMs]

There appears to be no advantage to obtaining FIT more often than every three years.

Dec 15, 2012 Issue
ACP Releases Best Practice Advice on Colorectal Cancer Screening [Practice Guidelines]

The American College of Physicians (ACP) recently reviewed guidelines on colorectal cancer screening available from the American Cancer Society/U.S. Multi-Society Task Force on Colorectal Cancer/American College of Radiology, Institute for Clinical Systems Improvement, U.S. Preventive Services Task ...

Apr 15, 2010 Issue
Screening for Colorectal Cancer: Recommendation Statement [U.S. Preventive Services Task Force]

The U.S. Preventive Services Task Force (USPSTF) recommends screening for colorectal cancer in adults using fecal occult blood test (FOBT), sigmoidoscopy, or colonoscopy, beginning at 50 years of age and continuing until 75 years of age. The risks and benefits of these screening methods vary.

Apr 15, 2010 Issue
Screening for Colorectal Cancer [Putting Prevention into Practice]

Case study: N.P., a 51-year-old man, comes to your office because one of his friends was recently diagnosed with colorectal cancer. He is wondering whether he should be screened too.

Sep 15, 2009 Issue
ACG Guidelines for Colorectal Cancer Screening [Practice Guidelines]

The American College of Gastroenterology (ACG) updated its recommendations on screening for colorectal cancer in 2008, and continues to support colonoscopy in average-risk patients every 10 years based on the evidence of effectiveness, cost-effectiveness, and patient acceptance.

Feb 15, 2009 Issue
Routine Aspirin or Nonsteroidal Anti-inflammatory Drugs for the Primary Prevention of Colorectal Cancer [Putting Prevention into Practice]

Case study: B.L., a 37-year-old Asian man, comes to your office for a physical examination. He mentions that he started taking a daily aspirin because he heard that it would reduce his risk of heart attack and colorectal cancer.

Dec 15, 2008 Issue
Colorectal Cancer: A Summary of the Evidence for Screening and Prevention [Article]

Colorectal cancer causes significant morbidity and mortality in the United States. The incidence of colorectal cancer can be reduced with increasing efforts directed at mass screening of average-risk adults 50 years and older. Currently, fecal occult blood test and flexible sigmoidoscopy have the hi...

Apr 1, 2008 Issue
Colonoscopy Surveillance After Polypectomy and Colorectal Cancer Resection [Article]

This article describes a joint update of guidelines by the American Cancer Society and the U.S. Multi-Society Task Force on Colorectal Cancer delineating evidence-based surveillance recommendations for patients after polypectomy and colorectal cancer resection. Although there are some qualifying con...

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