Oct 15, 2006 Issue
Lubiprostone (Amitiza) for Chronic Idiopathic Constipation [STEPS]

Although bulk or osmotic laxatives are less expensive first options for treating patients with chronic idiopathic constipation, lubiprostone is an alternative for those who do not tolerate or respond to these agents, or in patients older than 65 years in whom tegaserod use is not recommended.

Oct 15, 2006 Issue
Hirschsprung's Disease: Diagnosis and Management [Article]

Hirschsprung's disease (congenital megacolon) is caused by the failed migration of colonic ganglion cells during gestation. Varying lengths of the distal colon are unable to relax, causing functional colonic obstruction. Hirschsprung's disease most commonly involves the rectosigmoid region of the co...

Feb 1, 2006 Issue
Evaluation and Treatment of Constipation in Infants and Children [Article]

Constipation in children usually is functional and the result of stool retention. However, family physicians must be alert for red flags that may indicate the presence of an uncommon but serious organic cause of constipation, such as Hirschsprung's disease (congenital aganglionic megacolon), pseudo-...

Dec 1, 2005 Issue
Treatment of Constipation in Older Adults [Article]

Constipation is a common complaint in older adults. Although constipation is not a physiologic consequence of normal aging, decreased mobility and other comorbid medical conditions may contribute to its increased prevalence in older adults. Functional constipation is diagnosed when no secondary caus...

Mar 1, 2003 Issue
Childhood Constipation [Clinical Evidence Handbook]

What are the effects of treatments for childhood constipation?

Jun 1, 2002 Issue
Evaluation of Constipation [Article]

Constipation is the reason for 2.5 million physician visits per year in the United States, with more than one half of these visits to primary care physicians. Patients and physicians frequently define constipation differently. To determine the underlying cause of constipation, it is important to eva...

Sep 15, 1998 Issue
Constipation in the Elderly [Article]

Constipation affects as many as 26 percent of elderly men and 34 percent of elderly women and is a problem that has been related to diminished perception of quality of life. Constipation may be the sign of a serious problem such as a mass lesion, the manifestation of a systemic disorder such as hypo...

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