ITEMS IN AFP WITH KEYWORD:

Deep Venous Thrombosis

Jun 1, 2018 Issue
High-Dose vs. Standard-Dose Heparin for VTE Prophylaxis in Obese Patients [FPIN's Help Desk Answers]

In most patients weighing more than 220 lb (100 kg), high-dose heparin prophylaxis (7,500 units subcutaneously three times per day) does not further reduce the risk of VTE compared with standard-dose heparin (5,000 units subcutaneously two or three times per day).


Apr 15, 2018 Issue
Edoxaban (Savaysa) for the Prevention of Thromboembolic Events [STEPS]

Edoxaban is an alternative to warfarin and other oral anticoagulants for the prevention of stroke in patients with nonvalvular atrial fibrillation and for the treatment of deep venous thrombosis and pulmonary embolism.


Oct 15, 2017 Issue
Rivaroxaban vs. Warfarin for Treatment of DVT and PE [FPIN's Clinical Inquiries]

Rivaroxaban, along with the other factor Xa inhibitors, is as effective as or better in the short term (three months) than warfarin (Coumadin) for preventing recurrent DVT, nonfatal PE, and fatal PE, with no differences in mortality or bleeding events.


Jul 15, 2017 Issue
Greater Benefit with Rivaroxaban Than Aspirin for Extended Treatment of VTE [POEMs]

Compared with aspirin, the use of rivaroxaban (Xarelto) to extend anticoagulation beyond the initial six to 12 months to treat provoked or unprovoked VTE reduces the risk of recurrent symptomatic VTE without increasing the risk of bleeding. You would need to treat approximately 30 to 33 patients wit...


Mar 1, 2017 Issue
Deep Venous Thrombosis and Pulmonary Embolism: Current Therapy [Article]

Anticoagulation is the mainstay of therapy for venous thromboembolism. Most patients can be treated in the outpatient setting with low-molecular-weight heparin and a vitamin K antagonist (warfarin) or direct-acting oral anticoagulants.


Jan 1, 2016 Issue
Routine CT Scans for Occult Malignancy Not Useful in Patients with Unprovoked VTE [POEMs]

There is no advantage to adding CT of the abdomen and pelvis to a basic screening protocol for occult malignancy in patients with unprovoked VTE.


Nov 1, 2015 Issue
Continuing Warfarin for 18 Months After Unprovoked PE Reduces Risk of Recurrent VTE [POEMs]

Continuing warfarin therapy for 18 months after an unprovoked PE reduces the risk of recurrent symptomatic venous thromboembolism (VTE). However, benefit beyond 18 months is not maintained after the warfarin is discontinued.


Jun 15, 2015 Issue
Patients with Initial Unprovoked DVT or PE Benefit from Long-Term Low-Dose Aspirin [POEMs]

Aspirin improves long-term cardiovascular and thrombotic outcomes in patients who have had an initial unprovoked episode of VTE. The risk of bleeding was no higher in the aspirin group, perhaps because those at risk of bleeding were “uncovered” during the initial period of anticoagulation.


Apr 1, 2015 Issue
Optimal Treatment of Acute Venous Thromboembolism [POEMs]

This complex network meta-analysis of eight treatment regimens for acute venous thromboembolism found that a combination of unfractionated heparin and vitamin K antagonists is associated with the least effective strategy with the highest risk of recurrent events.


Apr 1, 2015 Issue
Thrombolysis for DVT: Has the Time Arrived? [AFP Journal Club]

Catheter-directed thrombolysis for proximal DVT is experimental but may be considered in a patient with phlegmasia and resulting compartment syndrome.


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