Mar 15, 2011 Issue
Donepezil to Manage Alzheimer Disease: New vs. Standard Dosing [AFP Journal Club]

Does donepezil benefit patients with Alzheimer disease, and is the new dosage superior to the standard dosage? This study showed benefit, but the data are misleading.

Dec 1, 2010 Issue
Frontotemporal Dementia: A Review for Primary Care Physicians [Article]

Frontotemporal dementia (FTD) is one of the most common forms of dementia in persons younger than 65 years. Variants include behavioral variant FTD, semantic dementia, and progressive nonfluent aphasia. Behavioral and language manifestations are core features of FTD, and patients have relatively pre...

Nov 1, 2010 Issue
AAN Updates Guidelines on Evaluating Driving Risk in Patients with Dementia [Practice Guidelines]

Quality Standards Subcommittee of the American Academy of Neurology (AAN) updated guidelines for the evaluation and management of driving risk in persons with dementia. The new evidence-based guidelines offer characteristics that can help to identify persons that are at risk of unsafe driving.

Mar 15, 2009 Issue
Brief Screening Instruments for Dementia in Primary Care [Point-of-Care Guides]

In addition to identifying patients who may benefit from pharmacotherapy, early detection of dementia helps families anticipate the patient’s needs and helps physicians identify those in need of additional support.

Apr 15, 2008 Issue
AAFP and ACP Release Guideline on Dementia Treatment [Practice Guidelines]

A guideline created by the American Academy of Family Physicians (AAFP) and the American College of Physicians (ACP) reviews the data on the effects of pharmacologic treatment of dementia for improving cognition, global function, behavior/mood, and quality of life (QOL)/activities of daily living (ADL).

Sep 1, 2006 Issue
Cholinesterase Inhibitors for Alzheimer's Disease [Cochrane for Clinicians]

Cholinesterase inhibitors produce a small benefit on several cognitive and noncognitive function scales. Although data for patients with severe dementia are sparse, there is no evidence to suggest a difference in effectiveness among patients with mild, moderate, or severe dementia. Compared with pla...

Aug 1, 2006 Issue
Are Atypical Antipsychotics Safe in Patients with Alzheimer's Disease? [Cochrane for Clinicians]

Although the atypical antipsychotic medications risperidone (Risperdal) and olanzapine (Zyprexa) are modestly efficacious in reducing aggression, routine use is not justified. Both drugs are associated with serious adverse cerebrovascular events and extrapyramidal symptoms. Use of atypical antipsych...

Apr 1, 2006 Issue
Dementia With Lewy Bodies: An Emerging Disease [Article]

Dementia with Lewy bodies appears to be the second most common form of dementia, accounting for about one in five cases. The condition is characterized by dementia accompanied by delirium, visual hallucinations, and parkinsonism. Other common symptoms include syncope, falls, sleep disorders, and dep...

Mar 15, 2006 Issue
Older Adult Drivers with Cognitive Impairment [Article]

As the number of drivers with cognitive impairment increases, family physicians are more likely to become involved in decisions about cessation of driving privileges in older patients. Physicians who care for cognitively impaired older adults should routinely ask about driving status. In patients wh...

Feb 15, 2006 Issue
Behavior Disorders of Dementia: Recognition and Treatment [Article]

Psychosis may pose a greater challenge than cognitive decline for patients with dementia and their caregivers. The nature and frequency of psychotic symptoms varies over the course of illness, but in most patients, these symptoms occur more often in the later stages of disease. Management of psychos...

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