Jun 1, 2005 Issue
FDA Warns Against Off-Label Use of Antipsychotic Drugs [Practice Guidelines]

May 1, 2005 Issue
Initial Evaluation of the Patient with Suspected Dementia [Article]

Dementia is a common disorder among older persons, and projections indicate that the number of patients with dementia in the United States will continue to grow. Alzheimer's disease and vascular dementia account for the majority of cases of dementia. After a thorough history and physical examination...

Nov 1, 2004 Issue
Donepezil in the Treatment of Vascular Dementia [Cochrane for Clinicians]

Donepezil in a dosage of 10 mg daily provides a small benefit in patients with mild to moderate vascular dementia and generally is well tolerated.

Oct 1, 2004 Issue
Screening for Dementia [Putting Prevention into Practice]

Case study: RG, a 75-year-old, college-educated man, presents for an annual physical examination. His friend recently was diagnosed with Alzheimer’s disease. RG is concerned about his occasional memory lapses and is worried that he also has the disease.

Sep 15, 2004 Issue
Efficient Identification of Adults with Depression and Dementia [Article]

Family physicians must decide how to screen for depression or dementia and which patients to screen. Mental health questionnaires can be helpful. In practice-based screening, questionnaires are administered to all patients, regardless of risk status. In case-finding screening, questionnaires are adm...

Mar 15, 2004 Issue
Screening for Dementia: Recommendation and Rationale [U.S. Preventive Services Task Force]

This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for dementia and the supporting evidence, and it updates the 1996 recommendations contained in the Guide to Clinical Preventive Services, second edition.

Oct 1, 2003 Issue
Pharmacologic Treatment of Alzheimer's Disease: An Update [Article]

Alzheimer's disease is characterized by the development of senile plaques and neurofibrillary tangles, which are associated with neuronal destruction, particularly in cholinergic neurons. Drugs that inhibit the degradation of acetylcholine within synapses are the mainstay of therapy. Donepezil, riva...

Sep 1, 2003 Issue
Gingko Biloba [Article]

Ginkgo biloba is commonly used in the treatment of early-stage Alzheimer's disease, vascular dementia, peripheral claudication, and tinnitus of vascular origin. Multiple trials investigating the efficacy of ginkgo for treating cerebrovascular disease and dementia have been performed, and systematic ...

Jun 1, 2003 Issue
Use of Atypical Antipsychotics in Patients with Dementia [Article]

Increasingly, atypical antipsychotic drugs are prescribed for elderly patients with symptoms of psychosis and behavioral disturbances. These symptoms often occur in patients with Alzheimer's disease, other dementias, or Parkinson's disease. As the average age of Americans increases, the prevalence o...

Jun 15, 2002 Issue
Guidelines for Managing Alzheimer's Disease: Part II. Treatment [Article]

Once the clinical diagnosis of Alzheimer's disease has been made, a treatment plan must be developed. This plan should include cholinesterase inhibitor therapy to temporarily improve cognition or slow the rate of cognitive decline, management of comorbid conditions, treatment of behavioral symptoms ...

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