Depression and Bipolar Disorder

Feb 1, 2020 Issue
Adverse Events of Pharmacologic Treatments of Major Depression in Older Adults [Implementing AHRQ Effective Health Care Reviews]

What are the adverse events of antidepressants prescribed to treat major depressive disorder in adults 65 years and older?

Dec 15, 2019 Issue
Augmentation of Antidepressant Treatment Offers Little Benefit [POEMs]

The available evidence that treatment-resistant depression (depression that is unresponsive to two different treatments of adequate dose and length) responds well to augmentation treatment (i.e., adding psychotherapy, lithium, or aripiprazole [Abilify] to current treatment) is weak.

Nov 15, 2019 Issue
Depression in Children and Adolescents: Evaluation and Treatment [Article]

Children older than 12 years should be screened for depression annually using a validated instrument. Although mild depression is often self-limited and can be managed with monitoring and support, persistent or more severe depression should be treated with psychotherapy and an antidepressant. These therapies used concurrently are more effective than either treatment alone.

Oct 1, 2019 Issue
Perinatal Depression: AAP Policy Statement on Recognition and Management [Practice Guidelines]

The American Academy of Pediatrics has released a policy statement regarding the integration of perinatal depression recognition and management into well-child visits.

Sep 15, 2019 Issue
Interventions to Prevent Perinatal Depression: Recommendation Statement [U.S. Preventive Services Task Force]

The USPSTF recommends that clinicians provide or refer pregnant and postpartum persons who are at increased risk of perinatal depression to counseling interventions.

Sep 15, 2019 Issue
Weak Evidence Supports Augmentation Therapy for Treatment-Resistant Depression [POEMs]

There is weak research to guide treatment decisions for patients who have not responded to two adequate courses of antidepressant treatment. One study of cognitive behavior therapy showed benefit over placebo.

Sep 15, 2019 Issue
Can We Prevent Perinatal Depression in the Primary Care Office? [Editorials]

Even if we do not provide maternity care, our commitment to the total care of our patients, which includes addressing behavioral medicine needs, allows us to be the ideal physicians to champion interventions to prevent perinatal depression.

Sep 15, 2019 Issue
Interventions to Prevent Perinatal Depression [Putting Prevention into Practice]

A 25-year-old woman presents to your office after having recently missed her period. A urine pregnancy test confirms that she is pregnant. She takes acyclovir for suppression of genital herpes, which she acquired as a teenager. She reports a history of depression and sexual abuse during adolescence....

Aug 15, 2019 Issue
Cognitive Behavior Therapy for Postpartum Depression [FPIN's Help Desk Answers]

In women with postpartum depression, the addition of CBT reduces depressive symptoms more effectively than usual care alone (medication and other therapies), with a medium effect size at the end of the intervention and a residual small effect size six months later.

Jun 15, 2019 Issue
Depression After ACS Events: AAFP Releases Updated Guidelines [Practice Guidelines]

The American Academy of Family Physicians has released a guideline focusing on depression in adults within three months of an ACS event (unstable angina or myocardial infarction). The guideline is based on a systematic review of randomized controlled trials and observational studies and covers screening and treatment.

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