Depression and Bipolar Disorder

Aug 15, 2013 Issue
Vilazodone (Viibryd) for the Treatment of Depression [STEPS]

The available evidence does not support the routine use of vilazodone in the treatment of depression. It is significantly more expensive than generic alternatives and is no more effective for moderate to severe depression than selective serotonin reuptake inhibitors or tricyclic antidepressants.

Dec 15, 2012 Issue
Depression in Children and Adolescents [Clinical Evidence Handbook]

What are the effects of pharmacological and psychological treatments for depression in children and adolescents? What are the effects of combination and complementary treatments for depression in children and adolescents? What are the effects of treatments for refractory depression in children and adolescents?

Dec 1, 2012 Issue
Seasonal Affective Disorder [Article]

Seasonal affective disorder is a combination of biologic and mood disturbances with a seasonal pattern, typically occurring in the autumn and winter with remission in the spring or summer. In a given year, about 5 percent of the U.S. population experiences seasonal affective disorder, with symptoms ...

Sep 1, 2012 Issue
Treatment of Childhood and Adolescent Depression [Article]

Major depressive disorder in children and adolescents is a common condition that affects physical, emotional, and social development. Risk factors include a family history of depression, parental conflict, poor peer relationships, deficits in coping skills, and negative thinking. Diagnostic criteria...

Aug 1, 2012 Issue
Managing Grief and Depression at the End of Life [Article]

Psychological distress is common in terminally ill persons and can be a source of great suffering. Grief is an adaptive, universal, and highly personalized response to the multiple losses that occur at the end of life. This response may be intense early on after a loss manifesting itself physically,...

Aug 1, 2012 Issue
Differentiating Grief and Depression in Patients Who Are Seriously Ill [Editorials]

Differentiating between grief and depression in a patient who is seriously ill is important because the management strategies for each condition are different. It can be difficult to distinguish between depression and grief because they have overlapping symptoms (i.e., sadness, crying, loss of appetite, weight, sleep) and may coexist.

Apr 1, 2012 Issue
Integrating Cognitive Behavioral Therapy into Management of Depression [Editorials]

Cognitive behavioral therapy (CBT) is a well-established, scientifically proven treatment for patients with depression. For family physicians to take full advantage of this treatment, they must be able to understand the nature and application of CBT; access professional resources that support effect...

Jan 15, 2012 Issue
Screening for Depression [Article]

In the United States, depression affects up to 9 percent of patients and accounts for more than $43 billion in medical care costs. The U.S. Preventive Services Task Force recommends screening in adolescents and adults in clinical practices that have systems in place to ensure accurate diagnosis, eff...

Nov 15, 2011 Issue
Clinical Vignettes in Geriatric Depression [Article]

The diagnosis of depression in older patients is often complicated by comorbid conditions, such as cerebrovascular disease or dementia. Tools specific for this age group, such as the Geriatric Depression Scale or the Cornell Scale for Depression in Dementia, may assist in making the diagnosis. Treat...

Oct 15, 2011 Issue
Premenstrual Syndrome and Premenstrual Dysphoric Disorder [Article]

Premenstrual syndrome is defined as recurrent moderate psychological and physical symptoms that occur during the luteal phase of menses and resolve with menstruation. It affects 20 to 32 percent of premenopausal women. Women with premenstrual dysphoric disorder experience affective or somatic sympto...

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