Depression and Bipolar Disorder

Feb 1, 2003 Issue
Depression in Children and Adolescents [Clinical Evidence Handbook]

What are the effects of treatments for depression in children and adolescents? Which treatments are effective to improve long-term outcomes?

Feb 1, 2003 Issue
Antidepressants: Update on New Agents and Indications [Article]

A number of antidepressants have emerged in the U.S. market in the past two decades. Selective serotonin reuptake inhibitors have become the drugs of choice in the treatment of depression, and they are also effective in the treatment of obsessive-compulsive disorder, panic disorder, and social phobi...

Oct 1, 2002 Issue
Diagnosis and Treatment of Premenstrual Dysphoric Disorder [Article]

From 2 to 10 percent of women of reproductive age have severe distress and dysfunction caused by premenstrual dysphoric disorder, a severe form of premenstrual syndrome. Current research implicates mechanisms of serotonin as relevant to etiology and treatment. Patients with mild to moderate symptoms...

Sep 15, 2002 Issue
Screening for Depression Across the Lifespan: A Review of Measures for Use in Primary Care Settings [Article]

Depression is a common psychiatric disorder in children, adolescents, adults, and the elderly. Primary care physicians, not mental health professionals, treat the majority of patients with symptoms of depression. Persons who are depressed have feelings of sadness, loneliness, irritability, worthless...

Aug 15, 2002 Issue
Screening for Depression: Recommendations and Rationale [U.S. Preventive Services Task Force]

This statement summarizes the current U.S. Preventive Services Task Force (USPSTF) recommendations for screening for depression and the supporting scientific evidence and it updates the 1996 recommendations in the Guide to Clinical Preventive Services, second edition.

Apr 1, 2002 Issue
Depressive Disorders [Clinical Evidence Handbook]

What are the effects of treatments for depressive disorders? What are the effects of continuation treatment with antidepressant drugs? Which treatments are most effective at improving long-term outcome?

Mar 1, 2002 Issue
Identifying and Managing Preparatory Grief and Depression at the End of Life [Article]

Grief and depression present similarly in patients who are dying. Conventional symptoms (e.g., frequent crying, weight loss, thoughts of death) used to assess for depression in these patients may be imprecise because these symptoms are also present in preparatory grief and as a part of the normal dy...

Aug 15, 2001 Issue
Assessment and Treatment of Depression Following Myocardial Infarction [Article]

Approximately 65 percent of patients with acute myocardial infarction report experiencing symptoms of depression. Major depression is present in 15 to 22 percent of these patients. Depression is an independent risk factor in the development of and mortality associated with cardiovascular disease in ...

Nov 15, 2000 Issue
Depression in Children and Adolescents [Article]

Depression among children and adolescents is common but frequently unrecognized. It affects 2 percent of prepubertal children and 5 to 8 percent of adolescents. The clinical spectrum of the disease can range from simple sadness to a major depressive or bipolar disorder. Risk factors include a family...

Sep 1, 2000 Issue
Alternative Therapies: Part 1. Depresssion, Diabetes, Obesity [Article]

Natural supplements are widely used in the United States and, while claims of their therapeutic effects abound, medical research does not always support their effectiveness. St. John's wort acts as a weak selective serotonin reuptake inhibitor with fewer side effects. S-Adenosylmethionine (SAMe) has...

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