ITEMS IN AFP WITH KEYWORD:
Semaglutide can be added to existing treatment to improve glycemic control and induce weight loss. It may also protect against cardiovascular outcomes in patients with type 2 diabetes and established cardiovascular disease.
In this study, there was no significant difference in the likelihood of a composite vascular outcome or all-cause mortality in patients given an omega-3 fatty acid supplement compared with those given an olive oil placebo.
Diabetic kidney disease (DKD) is associated with higher cardiovascular and all-cause morbidity and mortality. Screening is best done with annual spot urine albumin/creatinine ratio testing. Treatment includes management of hyperglycemia, hypertension, hyperlipidemia, and cessation of tobacco use. Blood pressure should be monitored. Several medications may help prevent or slow progression of DKD. Patients who progress to at least stage 3 DKD may benefit from referral to nephrology subspecialists.
The 7,740 patients who took low-dose aspirin experienced 51 fewer vascular deaths, nonfatal myocardial infarctions, or nonfatal ischemic strokes; 29 fewer transient ischemic attacks; and 44 fewer revascularizations than patients who took placebo over a mean of 7.4 years.
Through clinical and system-level interventions, family physicians can push back against the high cost of insulin and help patients with type 2 diabetes afford these essential medications.
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
The first-line treatment option for type 2 diabetes mellitus, metformin, is safe and fairly well-tolerated, has excellent long-term effectiveness on patient-oriented outcomes, is moderately priced, and has a simple dosing regimen. When more than one medication is required, the STEPS approach can help choose subsequent medications.
This study found that compared with expensive long-acting insulin analogs costing two to 10 times as much, NPH insulin results in a similar number of episodes of severe hypoglycemia (if not fewer) that result in emergency department visits and hospitalizations.
Dec 1, 2018 Issue
Preventing or Delaying Type 2 Diabetes Mellitus with Diet and Exercise [Cochrane for Clinicians]
There is moderate-quality evidence that in patients with impaired glucose tolerance (IGT) defined by an abnormal 75-g two-hour glucose tolerance test, implementing changes in diet and adding physical activity together can prevent or delay the development of type 2 diabetes.
The prevalence of type 2 diabetes mellitus in children and adolescents has increased worldwide with the obesity epidemic, and minorities are disproportionately affected. Find out who should be screened, when to begin screening, and recommended management strategies for younger patients.