Nov 15, 2020 Issue
Oral Semaglutide (Rybelsus) for the Treatment of Type 2 Diabetes Mellitus [STEPS]

Oral semaglutide (Rybelsus) is labeled as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus

Nov 15, 2020 Issue
Evidence to Avoid Overtesting and Overuse in Diabetes Mellitus and Other Diseases [Editorials]

What can physicians do to avoid overuse? Start by asking the right questions.

Nov 1, 2020 Issue
Metformin to Prevent Diabetes in Patients at Increased Risk [Cochrane for Clinicians]

In patients at increased risk of developing type 2 diabetes, metformin reduces the risk (number needed to treat [NNT] = 7; 95% CI, 6 to 10) compared with counseling on standard diet and exercise.

Oct 15, 2020 Issue
Cycled Hyperbaric Oxygen Improves the Healing of Diabetic Foot Ulcers [POEMs]

Hyperbaric oxygen provided with a device that cycles oxygen from high pressure to low pressure increased the likelihood of complete healing of diabetic foot ulcers when combined with standard dressing and an offloading boot.

Sep 15, 2020 Issue
Similar Long-Term Morbidity and Mortality with Human Insulin and Analogue Insulin [POEMs]

This study found no difference in long-term patient-oriented outcomes between human and analogue insulins in adults with type 2 diabetes.

Jun 1, 2020 Issue
Continuous Glucose Monitoring in Type 2 Diabetes Is Not Ready for Widespread Adoption [Editorials]

Although continuous glucose monitoring may benefit patients with type 1 diabetes mellitus, there is limited evidence that it offers similar benefits in patients with type 2 diabetes, regardless of whether they are taking insulin.

Mar 1, 2020 Issue
Linagliptin and Glimepiride Equally Effective for Adults with Type 2 Diabetes Mellitus [POEMs]

This study found that linagliptin is noninferior to glimepiride for reducing the risk of cardiovascular death, myocardial infarction, and stroke in adults with type 2 diabetes at an increased risk of cardiovascular disease.

Mar 1, 2020 Issue
IDx-DR for Diabetic Retinopathy Screening [Diagnostic Tests: What Physicians Need to Know]

IDx-DR is a reliable screening tool used to diagnose diabetic retinopathy in the primary care office and may reduce barriers to screening and improve gaps in eye care for those with diabetes.

Aug 1, 2019 Issue
Dapagliflozin in High-Risk Type 2 Diabetes Reduces Hospitalization for Heart Failure But Does Not Reduce Death, Myocardial Infarction, or Stroke [POEMs]

The only cardiovascular benefit to treatment with dapagliflozin was a reduction in the likelihood of hospitalization; 125 patients would need to be treated for 10 years to prevent one hospitalization.

Aug 1, 2019 Issue
Should Adults with Prediabetes Be Prescribed Metformin to Prevent Diabetes Mellitus? No: Evidence Does Not Show Improvements in Patient-Oriented Outcomes [Editorials: Controversies in Family Medicine]

Discussing with patients the pros and cons of medications for borderline glucose values could distract us from more important topics such as lifestyle changes, smoking cessation, and blood pressure control. Time is the most valuable resource in a physician-patient partnership, and there are better ways to spend it.

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