Dec 15, 2000 Issue
Attenuating Cardiovascular Risk Factors in Patients with Type 2 Diabetes [Article]

Patients with type 2 diabetes (formerly known as non-insulin-resistant diabetes) have a significantly increased risk of developing cardiovascular disease. Once clinical cardiovascular disease develops, these patients have a poorer prognosis than normoglycemic patients. By inducing endothelial change...

Sep 1, 2000 Issue
Alternative Therapies: Part 1. Depresssion, Diabetes, Obesity [Article]

Natural supplements are widely used in the United States and, while claims of their therapeutic effects abound, medical research does not always support their effectiveness. St. John's wort acts as a weak selective serotonin reuptake inhibitor with fewer side effects. S-Adenosylmethionine (SAMe) has...

Jan 15, 2000 Issue
AHA Examines Cardiovascular Problems in Diabetes [Practice Guidelines]

The American Heart Association (AHA) has issued recommendations for interventions to reduce the risk of cardiovascular complications in patients with diabetes mellitus.

Jan 1, 2000 Issue
Why Can't This Patient Take Insulin? [Curbside Consultation]

One of the prevailing challenges for physicians is dealing with noncompliant patients—those patients who seem unable or unwilling to comply with their treatment plan. When faced with such a patient, the physician's first impulse is frequently one of anger and frustration. The reasons for these feeli...

Dec 01, 1999 Issue
Oral Pharmacologic Management of Type 2 Diabetes [Article]

Epidemiologic and interventional studies have led to lower treatment targets for type 2 diabetes (formerly known as non-insulin-dependent diabetes), including a glycosylated hemoglobin level of 7 percent or less and a before-meal blood glucose level of 80 to 120 mg per dL (4.4 to 6.7 mmol per L). Ne...

Nov 15, 1999 Issue
Type 1 Diabetes Mellitus and the Use of Flexible Insulin Regimens [Article]

The management of type 1 diabetes mellitus (formerly known as insulin-dependent diabetes) has changed dramatically over the past 30 years. In particular, new insulin strategies have improved the ability to maintain near-normal glycemia. Factors such as onset, peak and duration of action can influenc...

Nov 1, 1999 Issue
Educational Guidelines for Achieving Tight Control and Minimizing Complications of Type 1 Diabetes [Article]

Tight glucose control with intensive therapy in patients with type 1 diabetes (formerly known as juvenile-onset or insulin-dependent diabetes) can delay the onset and slow the progression of retinopathy, nephropathy and neuropathy. Optimal blood glucose control is defined by a target glycosylated he...

Oct 1, 1999 Issue
Management of the Hyperosmolar Hyperglycemic Syndrome [Article]

Hyperglycemic hyperosmolarity is part of a clinical spectrum of severe hyperglycemic disorders ranging from pure hyperglycemic hyperosmolarity without ketosis to diabetic ketoacidosis, with significant overlap in the middle. From 50 to 75 percent of hospitalizable patients who have uncontrolled diab...

Aug 01, 1999 Issue
Management of Diabetic Ketoacidosis [Article]

Diabetic ketoacidosis is an emergency medical condition that can be life-threatening if not treated properly. The incidence of this condition may be increasing, and a 1 to 2 percent mortality rate has stubbornly persisted since the 1970s. Diabetic ketoacidosis occurs most often in patients with type...

May 15, 1999 Issue
Treatment of Type 2 Diabetes Mellitus [Article]

Type 2 diabetes mellitus (formerly called non-insulin-dependent diabetes) causes abnormal carbohydrate, lipid and protein metabolism associated with insulin resistance and impaired insulin secretion. Insulin resistance is a major contributor to progression of the disease and to complications of diab...

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