Feb 15, 2019 Issue
Type 2 Diabetes Therapies: A STEPS Approach [Article]

The first-line treatment option for type 2 diabetes mellitus, metformin, is safe and fairly well-tolerated, has excellent long-term effectiveness on patient-oriented outcomes, is moderately priced, and has a simple dosing regimen. When more than one medication is required, the STEPS approach can help choose subsequent medications.

Jan 1, 2019 Issue
NPH Insulin: Fewer Episodes of Severe Hypoglycemia Than Analogs and Less Than One-Half the Cost [POEMs]

This study found that compared with expensive long-acting insulin analogs costing two to 10 times as much, NPH insulin results in a similar number of episodes of severe hypoglycemia (if not fewer) that result in emergency department visits and hospitalizations.

Dec 1, 2018 Issue
Preventing or Delaying Type 2 Diabetes Mellitus with Diet and Exercise [Cochrane for Clinicians]

There is moderate-quality evidence that in patients with impaired glucose tolerance (IGT) defined by an abnormal 75-g two-hour glucose tolerance test, implementing changes in diet and adding physical activity together can prevent or delay the development of type 2 diabetes.

Nov 1, 2018 Issue
Type 2 Diabetes Mellitus in Children [Article]

The prevalence of type 2 diabetes mellitus in children and adolescents has increased worldwide with the obesity epidemic, and minorities are disproportionately affected. Find out who should be screened, when to begin screening, and recommended management strategies for younger patients.

Nov 1, 2018 Issue
Type 2 Diabetes Mellitus: ACP Releases Updated Guidance Statement on A1C Targets for Pharmacologic Glycemic Control [Practice Guidelines]

This guidance statement from the American College of Physicians (ACP) aims to help physicians achieve appropriate A1C targets via medication for nonpregnant patients with type 2 diabetes based on a review of six health care organization guidelines.

Aug 1, 2018 Issue
Diabetes: ADA Releases Revised Position Statement on Standards of Medical Care [Practice Guidelines]

Because the evidence regarding medical care for persons with diabetes mellitus continues to evolve, the American Diabetes Association (ADA) annually updates its standards. In addition, starting in 2018, the ADA will also periodically update its guidance online if warranted.

Aug 1, 2018 Issue
Type 1 Diabetes: Management Strategies [Article]

Patients with type 1 diabetes should maintain tight glycemic control to prevent complications. Frequent self-monitoring of blood glucose levels leads to improved A1C levels. Insulin administration via multiple daily injections or an insulin pump is effective. Physicians should educate patients about lifestyle management, recognition of hypoglycemia, and proper care during sick days.

May 1, 2018 Issue
Top 20 Research Studies of 2017 for Primary Care Physicians [Article]

The latest installment of the top 20 research studies for primary care physicians includes studies on cardiovascular disease and hypertension, infections, diabetes mellitus, musculoskeletal problems, and cancer screening, among other topics. The five highest-rated practice guidelines are also summarized.

Apr 1, 2018 Issue
DPP-4 Inhibitors and GLP-1 Receptor Agonists for Prevention or Delay of Type 2 Diabetes Mellitus and Associated Complications [Cochrane for Clinicians]

There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo (number needed to harm [NNH] = 42).

Feb 15, 2018 Issue
Diabetes Education and Glycemic Control [FPIN's Clinical Inquiries]

Counseling by a diabetes educator or a team of educators delivered in a variety of formats may reduce A1C levels by 0.2% to 0.8% compared with usual care alone. Diabetes educators should be considered for patients who have higher baseline A1C levels (8% to 9%) because this group had greater improvem...

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