Oct 15, 2014 Issue
Bariatric Surgery Plus Intensive Medical Therapy Is Better Than Medical Therapy Alone for Diabetes [POEMs]

Bariatric surgery in conjunction with intensive medical therapy results in significantly enhanced glycemic control at three years compared with medical therapy alone, as well as better weight control, less use of glucose-lowering medications, and improved quality of life.

Sep 15, 2014 Issue
Rosiglitazone, Medical Reversal, and Back to Basics for Diabetes [Editorials]

For too long, the debate in diabetes has centered on the question: Is this medication harmful? It's time to revisit the more fundamental question: Is this treatment beneficial?

Sep 1, 2014 Issue
ACE Inhibitors Decrease Cardiovascular Events in Patients with Diabetes, ARBs Do Not [POEMs]

In patients with diabetes, ACE inhibitors decrease cardiovascular events and all-cause mortality. ARBs do not. Both drug classes decrease heart failure incidence. Although both drug classes have been available for almost 15 years, there is only one study of 250 patients that directly compared their ...

May 15, 2014 Issue
Glycemic Control in Type 2 Diabetes (Drug Treatments) [Clinical Evidence Handbook]

What are the effects of blood glucose–lowering medications in adults with type 2 diabetes?

Feb 15, 2014 Issue
“Lending a Hand” to Patients with Type 2 Diabetes: A Simple Way to Communicate Treatment Goals [Editorials]

A new approach to the care of adults with type 2 diabetes emphasizes proven interventions that improve duration and quality of life.

Jan 15, 2014 Issue
Fewer Deaths/Strokes/Revascularizations with Metformin Than Glipizide [POEMs]

Over five years, treatment with metformin for three years, with other hypoglycemics as needed, reduced the likelihood of death, nonfatal stroke, or the need for vascularization compared with treatment beginning with glipizide (Glucotrol). Cardiovascular events were not individually reduced with metformin compared with glipizide.

Dec 15, 2013 Issue
Intensive Lifestyle Intervention Fails to Improve Patient-Oriented Outcomes in Persons with Obesity and Diabetes [POEMs]

This large, well-designed trial failed to find a statistically significant improvement in patient-oriented outcomes in patients with diabetes, despite a fairly intensive lifestyle intervention and long-term follow-up.

Nov 15, 2013 Issue
AAP Releases Guideline on Managing Type 2 Diabetes Mellitus in Patients 10 to 18 Years of Age [Practice Guidelines]

Childhood type 2 diabetes poses a challenge to many physicians who are not used to treating this disease in such young patients. The American Academy of Pediatrics (AAP) has released a guideline of evidence-based recommendations for treating type 2 diabetes in patients 10 to 18 years of age. The gui...

Sep 1, 2013 Issue
Aliskiren Worsens Outcomes in High-Risk Patients with Diabetes [POEMs]

Aliskiren increases the likelihood of adverse cardiovascular outcomes in patients with diabetes and kidney or heart disease, and cannot be recommended.

Aug 1, 2013 Issue
Diabetic Foot Infections [Article]

Diabetic foot infection, defined as soft tissue or bone infection below the malleoli, is the most common complication of diabetes mellitus leading to hospitalization and the most frequent cause of nontraumatic lower extremity amputation. Diabetic foot infections are diagnosed clinically based on the...

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