Jun 15, 2010 Issue
Saxagliptin (Onglyza) for Type 2 Diabetes Mellitus [STEPS]

Saxagliptin lowers A1C levels to a lesser extent and is much more expensive than first-line therapy with metformin. Its ability to decrease diabetes-related complications, including mortality, is not known. It is a DPP-4 inhibitor that has a more significant drug interaction profile than sitagliptin and offers little cost advantage.

May 1, 2010 Issue
Glycemic Control in the Hospital: What to Do When Experts Disagree [Editorials]

May 1, 2010 Issue
Glucose Control in Hospitalized Patients [Article]

Evidence indicates that hospitalized patients with hyperglycemia do not benefit from tight blood glucose control. Maintaining a blood glucose level of less than 180 mg per dL (9.99 mmol per L) will minimize symptoms of hyperglycemia and hypoglycemia without adversely affecting patient-oriented healt...

May 1, 2010 Issue
Glycemic Control in Hospitalized Patients Not in Intensive Care: Beyond Sliding-Scale Insulin [Article]

Glycemic control in hospitalized patients who are not in intensive care remains unsatisfactory. Despite persistent expert recommendations urging its abandonment, the use of sliding-scale insulin remains pervasive in U.S. hospitals. Evidence for the effectiveness of sliding-scale insulin is lacking a...

Apr 1, 2010 Issue
Diabetes Mellitus: Diagnosis and Screening [Article]

Based on etiology, diabetes is classified as type 1 diabetes mellitus, type 2 diabetes mellitus, latent autoimmune diabetes, maturity-onset diabetes of youth, and miscellaneous causes. The diagnosis is based on measurement of A1C level, fasting or random blood glucose level, or oral glucose toler...

Apr 1, 2010 Issue
Latent Autoimmune Diabetes in Adults [Editorials]

Jan 1, 2010 Issue
Retinal Changes and Visual Impairment [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

Nov 15, 2009 Issue
Joint Guideline on Intensive Glycemic Control and the Prevention of Cardiovascular Events [Practice Guidelines]

Recommendations from the American Diabetes Association (ADA), American College of Cardiology Foundation (ACC), and American Heart Association (AHA) for glycemic control and prevention of cardiovascular events in patients with diabetes.

Nov 15, 2009 Issue
Screening for Type 2 Diabetes Mellitus in Adults [Putting Prevention into Practice]

Case study: A 50-year-old woman with a history of hyperlipidemia visits your office for a physical examination. Her blood pressure is 140/82 mm Hg, and her body mass index is 30 kg per m2.

Nov 15, 2009 Issue
Screening for Type 2 Diabetes Mellitus in Adults: Recommendation Statement [U.S. Preventive Services Task Force]

The U.S. Preventive Services Task Force (USPSTF) recommends screening for type 2 diabetes mellitus in asymptomatic adults with sustained blood pressure (treated or untreated) greater than 135/80 mm Hg.

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