Jun 1, 2015 Issue
Individualizing Target Goals and Treatment in Patients with Type 2 Diabetes [POEMs]

This statement from American and European diabetes societies suggests that tighter control of hyperglycemia be attempted only in patients with a recent diagnosis and a low risk of hypoglycemia; who have a long life expectancy with few or no comorbidities, including cardiovascular disease; and who ar...

Jun 1, 2015 Issue
Tight Glycemic Control for Type 2 Diabetes Mellitus (Over Five Years) [Medicine by the Numbers]

Studies show that none were helped and 1 in 6 patients were harmed. See why.

Feb 15, 2015 Issue
Metformin Associated with Less Need for a Second Medicine [POEMs]

n this retrospective analysis, which benefits from large numbers of patients but suffers from possible biases, patients who initially took an oral hypoglycemic other than metformin (Glucophage) were significantly more likely to require a second oral agent.

Oct 15, 2014 Issue
Bariatric Surgery Plus Intensive Medical Therapy Is Better Than Medical Therapy Alone for Diabetes [POEMs]

Bariatric surgery in conjunction with intensive medical therapy results in significantly enhanced glycemic control at three years compared with medical therapy alone, as well as better weight control, less use of glucose-lowering medications, and improved quality of life.

Sep 15, 2014 Issue
Rosiglitazone, Medical Reversal, and Back to Basics for Diabetes [Editorials]

For too long, the debate in diabetes has centered on the question: Is this medication harmful? It's time to revisit the more fundamental question: Is this treatment beneficial?

Sep 1, 2014 Issue
ACE Inhibitors Decrease Cardiovascular Events in Patients with Diabetes, ARBs Do Not [POEMs]

In patients with diabetes, ACE inhibitors decrease cardiovascular events and all-cause mortality. ARBs do not. Both drug classes decrease heart failure incidence. Although both drug classes have been available for almost 15 years, there is only one study of 250 patients that directly compared their ...

May 15, 2014 Issue
Glycemic Control in Type 2 Diabetes (Drug Treatments) [Clinical Evidence Handbook]

What are the effects of blood glucose–lowering medications in adults with type 2 diabetes?

Feb 15, 2014 Issue
“Lending a Hand” to Patients with Type 2 Diabetes: A Simple Way to Communicate Treatment Goals [Editorials]

A new approach to the care of adults with type 2 diabetes emphasizes proven interventions that improve duration and quality of life.

Jan 15, 2014 Issue
Fewer Deaths/Strokes/Revascularizations with Metformin Than Glipizide [POEMs]

Over five years, treatment with metformin for three years, with other hypoglycemics as needed, reduced the likelihood of death, nonfatal stroke, or the need for vascularization compared with treatment beginning with glipizide (Glucotrol). Cardiovascular events were not individually reduced with metformin compared with glipizide.

Dec 15, 2013 Issue
Intensive Lifestyle Intervention Fails to Improve Patient-Oriented Outcomes in Persons with Obesity and Diabetes [POEMs]

This large, well-designed trial failed to find a statistically significant improvement in patient-oriented outcomes in patients with diabetes, despite a fairly intensive lifestyle intervention and long-term follow-up.

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