ITEMS IN AFP WITH KEYWORD:
Dec 15, 2010 Issue
Thiazolidinedione Therapy for Managing Metabolic Syndrome [FPIN's Clinical Inquiries]
There is no patient-oriented evidence supporting the use of TZD therapy in patients in the general population who have metabolic syndrome. Rosiglitazone (Avandia) use decreases cardiovascular morbidity and mortality in patients with metabolic syndrome who are undergoing coronary stenting.
Nov 1, 2010 Issue
Does Metformin Increase the Risk of Fatal or Nonfatal Lactic Acidosis? [Cochrane for Clinicians]
In patients without standard contraindications to metformin therapy, metformin does not increase the risk of lactic acidosis.
The 2010 American Diabetes Association's (ADA) “Standards of Medical Care in Diabetes” includes revisions based on new evidence. Several sections have undergone major changes.
Photo Quiz presents readers with a clinical challenge based on a photograph or other image.
Diabetic peripheral neuropathic pain affects the functionality, mood, and sleep patterns of approximately 10 to 20 percent of patients with diabetes mellitus. Treatment goals include restoring function and improving pain control. Patients can realistically expect a 30 to 50 percent reduction in disc...
Saxagliptin lowers A1C levels to a lesser extent and is much more expensive than first-line therapy with metformin. Its ability to decrease diabetes-related complications, including mortality, is not known. It is a DPP-4 inhibitor that has a more significant drug interaction profile than sitagliptin and offers little cost advantage.
Evidence indicates that hospitalized patients with hyperglycemia do not benefit from tight blood glucose control. Maintaining a blood glucose level of less than 180 mg per dL (9.99 mmol per L) will minimize symptoms of hyperglycemia and hypoglycemia without adversely affecting patient-oriented healt...
Glycemic control in hospitalized patients who are not in intensive care remains unsatisfactory. Despite persistent expert recommendations urging its abandonment, the use of sliding-scale insulin remains pervasive in U.S. hospitals. Evidence for the effectiveness of sliding-scale insulin is lacking a...
Based on etiology, diabetes is classified as type 1 diabetes mellitus, type 2 diabetes mellitus, latent autoimmune diabetes, maturity-onset diabetes of youth, and miscellaneous causes. The diagnosis is based on measurement of A1C level, fasting or random blood glucose level, or oral glucose toler...