ITEMS IN AFP WITH KEYWORD:
Drug Adverse Effects
Polypharmacy, commonly defined as the use of at least five medications, can have negative consequences for both the patient and health care system. Physicians should identify and prioritize medications to discontinue and discuss potential deprescribing with patients. A specific follow-up plan should be developed, including reviewing the patient’s medication list at every visit.
The limited rigorous data on deprescribing suggest that many patients can safely stop unnecessary medication, but symptom relapse is significant.
There are four important medication issues to discuss with patients as they get older. Find out more and learn the five steps to individualize deprescribing practices for each patient.
We want to assure all stakeholders of the rigorous approval process that supports the FDA's commitment to ensuring the high quality of generic drugs marketed in the United States.
A woman presented with an asymptomatic white patch on the right wrist that appeared two months earlier.
This study found that maternal antidepressant use during the first trimester of pregnancy is associated with an increased risk of preterm birth, but not SGA, ASD, or ADHD. Another study in the same issue also reported no increased risk of ASD with in utero exposure to selective serotonin reuptake in...
A woman with a long history of cocaine use presented to the emergency department with leg ulcers and ecchymoses on her ears.
For some drugs, risk mitigation measures beyond FDA-approved labeling are deemed necessary. Learn more about these Risk Evaluation and Mitigation Strategies (REMS).
A man presented with asymptomatic blue-gray lesions on both feet that were darkening over time. He was using several medications.
Mirtazapine (Remeron) and venlafaxine are associated with higher rates of completed suicide in primary care patients. Rates of suicide attempts and completion are similar with the use of selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants.