Drug Adverse Effects

Jul 15, 2012 Issue
The "ARB-MI Paradox": Real or a Fluke? [AFP Journal Club]

The Journal Club authors discuss what factors make this meta-analysis, designed to determine whether the ARB-MI paradox is real or a statistical fluke, successful.

Jul 1, 2012 Issue
Reducing Adverse Effects of Proton Pump Inhibitors [Article]

Proton pump inhibitors effectively treat gastroesophageal reflux disease, erosive esophagitis, duodenal ulcers, and pathologic hypersecretory conditions. Proton pump inhibitors cause few adverse effects with short-term use; however, long-term use has been scrutinized for appropriateness, drug-drug i...

Feb 15, 2012 Issue
The Importance of Physicians Identifying and Reporting Adverse Drug Events [Editorials]

By identifying and reporting adverse drug events, conscientious physicians may influence drug labeling or alerts that impact prescribing practices and help protect the public's health.

Aug 1, 2010 Issue
Acutely Swollen Tongue in a Middle-Aged Woman [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

May 1, 2010 Issue
Prevention, Recognition, and Management of Serotonin Syndrome [Article]

Serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the nervous system. It is characterized by mental status changes, autonomic instability, and neuromuscular hyperactivity. Most reported cases of serotonin syndrome are in patients using multip...

Mar 1, 2010 Issue
Adverse Effects of Antipsychotic Medications [Article]

The use of antipsychotic medications entails a difficult trade-off between the benefit of alleviating psychotic symptoms and the risk of troubling, sometimes life-shortening adverse effects. There is more variability among specific antipsychotic medications than there is between the first- and secon...

Feb 1, 2010 Issue
Boxed Warnings and Other FDA Communication Tools [Editorials]

Dec 15, 2009 Issue
NSAIDs and Cardiovascular Risk [Editorials]

Dec 15, 2009 Issue
NSAID Prescribing Precautions [Article]

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including significant upper gastrointestinal tract bleeding. Older persons, persons taking anticoagulants, and persons with a history of upper gastrointestinal tract bleeding associated with NS...

Oct 1, 2009 Issue
Gadolinium-Associated Nephrogenic Systemic Fibrosis [Article]

Nephrogenic systemic fibrosis is a progressive, potentially fatal multiorgan system fibrosing disease related to exposure of patients with renal failure to the gadolinium-based contrast agents used in magnetic resonance imaging. Because of this relationship between nephrogenic systemic fibrosis and ...

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