ITEMS IN AFP WITH KEYWORD:

Drug Adverse Effects

Oct 1, 2002 Issue
Adverse Reactions to Contrast Material. Recognition, Prevention and Treatment [Article]

Adverse reactions to contrast agents range from a mild inconvenience, such as itching associated with hives, to a life-threatening emergency. Renal toxicity is a well known adverse reaction associated with the use of intravenous contrast material. Other forms of adverse reactions include delayed all...


Aug 15, 2002 Issue
Benefits and Risks of Psychiatric Medications During Pregnancy [Article]

Traditionally, psychiatric medications were withheld during pregnancy because of fear of teratogenic and other effects. The emergence of evidence of the safety of most commonly used psychiatric medications, the availability of this information in the form of online databases, and the documentation o...


Apr 1, 2001 Issue
Blue-Gray Centrofacial Hyperpigmentation [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.


Mar 1, 2000 Issue
Appropriate Use of Psychotropic Drugs in Nursing Homes [Article]

The Omnibus Budget Reconciliation Act (OBRA) of 1987 limited the use of psychotropic medications in residents of long-term care facilities. Updates of OBRA guidelines have liberalized some dosing restrictions, but documentation of necessity and periodic trials of medication withdrawal are still emph...


Sep 1, 1999 Issue
Back Rash [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.


Feb 15, 1998 Issue
Isoniazid Overdose: Recognition and Treatment [Article]

Since isoniazid is increasingly being used to control the spread of tuberculosis, physicians must be aware of its potentially fatal effects. The ingestion of toxic amounts of isoniazid causes recurrent seizures, profound metabolic acidosis, coma and even death. In adults, toxicity can occur with the...


Jan 1, 1998 Issue
Cytochrome P450: New Nomenclature and Clinical Implications [Article]

Many drug interactions are a result of inhibition or induction of cytochrome P450 enzymes (CYP450). The CYP3A subfamily is involved in many clinically significant drug interactions, including those involving nonsedating antihistamines and cisapride, that may result in cardiac dysrhythmias. CYP3A4 an...


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