ITEMS IN AFP WITH KEYWORD:

Drug Therapy

Apr 15, 2018 Issue
Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women [Putting Prevention into Practice]

D.M. is a 52-year-old woman who presents to your office for a well-woman visit. She has been menopausal since 50 years of age and has no significant medical or surgical history. She is up to date on her recommended screenings, with normal mammography and colonoscopy results, and has no history of an...


Apr 15, 2018 Issue
Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: Recommendation Statement [U.S. Preventive Services Task Force]

The USPSTF recommends against the use of combined estrogen and progestin for the primary prevention of chronic conditions in postmenopausal women and the use of estrogen alone for the primary prevention of chronic conditions in postmenopausal women who have had a hysterectomy.


Apr 1, 2018 Issue
Broad-Spectrum Antibiotics Increase Adverse Events in Children with Acute Respiratory Infections with Minimal Benefit [POEMs]

Broad-spectrum antibiotics are no more effective than narrow-spectrum antibiotics for treating acute respiratory tract infections in infants and children, and adverse events are significantly more common in children treated with broad-spectrum antibiotics.


Apr 1, 2018 Issue
Duration of Bisphosphonate Therapy [FPIN's Help Desk Answers]

Oral bisphosphonates significantly reduce clinical fracture risk at four years in women with postmenopausal osteoporosis (T-score less than −2.5). Treatment beyond five years is associated with further reductions in fractures in women with persistent femoral neck T-scores less than −2.5.


Mar 15, 2018 Issue
Ibuprofen and Morphine Provide Similar Post-op Pain Relief in Kids; Ibuprofen Has Fewer Harms [POEMs]

This carefully designed and adequately powered study found no difference in pain reduction between ibuprofen and oral morphine in children with postoperative pain. Adverse effects, however, were much more likely with morphine.


Mar 1, 2018 Issue
Ibuprofen Plus Acetaminophen Equals Opioid Plus Acetaminophen for Acute Severe Extremity Pain [POEMs]

In adults presenting to the emergency department with acute extremity pain severe enough to warrant radiologic investigation, ibuprofen plus acetaminophen was equally effective in reducing pain intensity at two hours compared with three different opioid and acetaminophen combination analgesics.


Feb 1, 2018 Issue
Beta Blockers Compared with Other Drug Options for the Treatment of Hypertension [Medicine by the Numbers]


Dec 15, 2017 Issue
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults [Putting Prevention into Practice]

L.D., a 66-year-old generally healthy white man, presents for his annual physical. He has no history of cardiovascular disease (CVD); he has had consistent systolic blood pressure measurements of 140 mm Hg; he is not taking any medications; he does not smoke; he exercises three times per week; and his body mass index is 25 kg per m2.


Nov 1, 2017 Issue
Tapering Patients Off of Benzodiazepines [Curbside Consultation]

When prescribed at a low dosage for a short time (fewer than 30 days), benzodiazepines can effectively treat generalized and social anxiety, panic disorder, and sleep disorders. Long-term use for anxiety and sleep disorders is not supported by research because it is associated with the development o...


Oct 15, 2017 Issue
Newer Oral Hypoglycemics Do Not Increase or Decrease Mortality [POEMs]

This seems like a strange question considering that the goal is to decrease mortality with drug therapy. Nevertheless, this study showed that the new kids on the diabetes block—exenatide (Byetta), dulaglutide (Trulicity), sitagliptin (Januvia), saxagliptin (Onglyza), and others—do not increase mortality, even in patients with cardiovascular risk.


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