Drug Therapy

Nov 15, 2004 Issue
Strategy to Strengthen Safeguards for Children Treated with Antidepressants [Practice Guidelines]

Aug 1, 2003 Issue
Off-Label Applications for SSRIs [Article]

Selective serotonin reuptake inhibitors (SSRIs) are widely used because of their safety, tolerability, and demonstrated efficacy across a broad range of clinical conditions. Medical literature supports the use of SSRIs for the treatment of many conditions outside of the indications approved by the U...

Jun 15, 2003 Issue
Over-the-Counter Medications in Pregnancy [Article]

Pregnant women commonly use over-the-counter medications. Although most over-the-counter drugs have an excellent safety profile, some have unproven safety or are known to adversely affect the fetus. The safety profile of some medications may change according to the gestational age of the fetus. Beca...

Feb 15, 2003 Issue
Antiviral Drugs in the Immunocompetent Host: Part I. Treatment of Hepatitis, Cytomegalovirus, and Herpes Infections [Article]

Feb 15, 2003 Issue
Antiviral Drugs in the Immunocompetent Host: Part II. Treatment of Influenza and Respiratory Syncytial Virus Infections [Article]

Family physicians should be familiar with the various drugs available for treating and preventing viral infections. Part II of this two-part article focuses on agents used to manage influenza and respiratory syncytial virus. Rimantadine and amantadine traditionally have been used to prevent and trea...

Nov 1, 2002 Issue
Aspirin for the Primary Prevention of Cardiovascular Events [Putting Prevention into Practice]

Case study: ST is a 55-year-old man who you see regularly for hypertension and depression. He is overweight and sedentary, and his elder sister recently had a heart attack. He asks you whether he should take a daily aspirin, “just in case.”

Aug 15, 2002 Issue
Benefits and Risks of Psychiatric Medications During Pregnancy [Article]

Traditionally, psychiatric medications were withheld during pregnancy because of fear of teratogenic and other effects. The emergence of evidence of the safety of most commonly used psychiatric medications, the availability of this information in the form of online databases, and the documentation o...

Jun 1, 2002 Issue
Significant FDA Approvals in 2001 [Practice Guidelines]

In 2001, the U.S. Food and Drug Administration (FDA) launched numerous initiatives to assure the availability of medical products for the treatment of injuries that could be caused by terrorists using biologic, chemical, or nuclear agents.

May 15, 2002 Issue
Aspirin for the Primary Prevention of Cardiovascular Events [U.S. Preventive Services Task Force]

This statement summarizes the current U.S. Preventive Services Task Force (USPSTF) recommendations for aspirin in the primary prevention of cardiovascular events and the supporting scientific evidence.

Feb 1, 2002 Issue
Quinolones: A Comprehensive Review [Article]

With the recent introduction of agents such as gatifloxacin and moxifloxacin, the traditional gram-negative coverage of fluoroquinolones has been expanded to include specific gram-positive organisms. Clinical applications beyond genitourinary tract infections include upper and lower respiratory infe...

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