Jan 15, 2020 Issue
Functional Dyspepsia: Evaluation and Management [Article]

Dyspepsia affects up to 30% of the general population in the United States, Canada, and the United Kingdom, with 70% of patients having functional dyspepsia. Symptoms include postprandial fullness, early satiety, and epigastric pain or burning. Perform a dyspepsia endoscopy for patients 60 years or older. For patients younger than 60 years, a test and treat strategy for Helicobacter pylori is recommended before acid suppression therapy. All patients should be advised to limit foods associated with increased symptoms of dyspepsia.

Sep 15, 2019 Issue
Cervical Cancer, Febrile Seizures, HIV Infection, Dyspepsia [AFP Clinical Answers]

Key clinical questions and their evidence-based answers directly from the journal's content, written by and for family physicians.

Mar 1, 2019 Issue
Gas, Bloating, and Belching: Approach to Evaluation and Management [Article]

Gas, bloating, and belching are primarily caused by functional gastrointestinal disorders; psychological distress can make symptoms worse. Exhaustive testing is not necessary for diagnosis. Most patients are classified as having gastric or small bowel bloating, bloating with constipation, or belching disorders. Patients with symptoms of irritable bowel syndrome should be tested for celiac disease; patients with chronic constipation should have a rectal examination. There is insufficient evidence to support the routine use of highly restrictive exclusion diets except in patients with confirmed celiac disease.

Aug 1, 2018 Issue
The Role of Proton Pump Inhibitor Therapy in Patients with Functional Dyspepsia [Cochrane for Clinicians]

There is moderate-quality evidence that PPIs are more effective than placebo at relieving overall symptoms in patients with functional dyspepsia (number needed to treat [NNT] = 11). Low-quality evidence suggests a small benefit of PPI therapy compared with prokinetics, and little to no benefit of PPI therapy vs. histamine H2 antagonists.

Mar 1, 2011 Issue
Update on the Evaluation and Management of Functional Dyspepsia [Article]

Dyspepsia affects up to 40 percent of adults each year and is often diagnosed as functional (nonulcer) dyspepsia. The defining symptoms are postprandial fullness, early satiation, or epigastric pain or burning in the absence of causative structural disease. These symptoms may coexist with symptoms o...

Jul 1, 2006 Issue
AGA Releases Updated Recommendations on Dyspepsia [Practice Guidelines]

The American Gastroenterological Association (AGA) has released a position statement to reflect new evidence on the evaluation of dyspepsia. The AGA defines dyspepsia as chronic or recurrent pain or discomfort in the upper abdomen.

Sep 15, 2003 Issue
Evaluation of Epigastric Discomfort and Management of Dyspepsia and GERD [Practice Guidelines]

The Institute for Clinical Systems Improvement (ICSI) recently published a guideline on the evaluation and management of dyspepsia and gastroesophageal reflux disease (GERD).

Nov 1, 2001 Issue
Symptomatic Treatment and H. pylori Eradication Therapy for Nonulcer Dyspepsia [Cochrane for Clinicians]

Bismuth subcitrate, histamine H2-receptor antagonists or proton pump inhibitors could be recommended for short-term relief of symptoms. Eradication of H. pylori would slightly decrease this patient's chance of having persistent symptoms over the next three to 12 months.

Oct 15, 1999 Issue
Evaluation and Management of Dyspepsia [Article]

Dyspepsia, often defined as chronic or recurrent discomfort centered in the upper abdomen, can be caused by a variety of conditions. Common etiologies include peptic ulcers and gastroesophageal reflux. Serious causes, such as gastric and pancreatic cancers, are rare but must also be considered. Symp...

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