Feb 01, 2022 Issue
Fever of Unknown Origin in Adults [Article]

Fever of unknown origin is defined as a clinically documented temperature of 101°F or higher on several occasions, coupled with an unrevealing diagnostic workup. The differential diagnosis is broad but is typically categorized as infection, malignancy, noninfectious inflammatory disease, or miscella...

May 1, 2021 Issue
Ibuprofen vs. Acetaminophen for Fever or Pain in Children Younger Than Two Years [Medicine by the Numbers]

A meta-analysis found that ibuprofen is more effective than acetaminophen in reducing fever and pain in children younger than two years, although further study is needed to evaluate combination therapy, dosing, and use in children younger than six months.

Jun 15, 2020 Issue
Management of Fever in Infants and Young Children [Article]

Febrile illness in children younger than 36 months is a concern with potentially serious consequences. Factors include poor arousability and increased respiratory effort. Urinary tract infections are the most common serious bacterial infections in these children. Antibiotic choice should reflect local patterns of microbial resistance.

Apr 15, 2020 Issue
Predicting the Likelihood of a Recurrent Febrile Seizure [Point-of-Care Guides]

In children presenting with a simple febrile seizure, is it possible to determine the likelihood of a recurrent febrile seizure?

Oct 1, 2019 Issue
Laboratory-Based Prediction Model Can Rule Out Serious Bacterial Infections in Febrile Infants [POEMs]

In febrile infants up to 60 days of age, the combination of a normal urinalysis result, an absolute neutrophil count of less than 4,090 per mL (4.1 × 109 per L), and a serum procalcitonin level of less than 1.71 ng per mL is accurate at ruling out serious bacterial infections.

Sep 15, 2019 Issue
Cervical Cancer, Febrile Seizures, HIV Infection, Dyspepsia [AFP Clinical Answers]

Key clinical questions and their evidence-based answers directly from the journal's content, written by and for family physicians.

Apr 1, 2019 Issue
Febrile Seizures: Risks, Evaluation, and Prognosis [Article]

Children who have a simple febrile seizure and are well-appearing usually do not require routine diagnostic testing. For children with complex seizures, the neurologic examination should guide further evaluation. given the benign nature of febrile seizures, the routine use of antiepileptics is not indicated because of adverse effects of these medications. Antipyretics do not decrease the risk of febrile seizures. Management consists of parent reassurance and education regarding home management of seizures.

Apr 15, 2017 Issue
Fever in Well-Appearing Children Younger Than Two Years: A Clinical Policy from the ACEP [Practice Guidelines]

The American College of Emergency Physicians (ACEP) has released a clinical policy addressing issues in children younger than two years who visit the emergency department with fever, but who appear well.

Jul 15, 2014 Issue
Prolonged Febrile Illness and Fever of Unknown Origin in Adults [Article]

To determine the underlying cause, begin the initial evaluation by looking for potentially diagnostic clues before proceeding to the minimum diagnostic workup.

Oct 15, 2013 Issue
Fever in Returning Travelers: A Case-Based Approach [Article]

Overall, 3% to 19% of travelers to the developing world will return to the United States with fever or will develop fever within weeks of their return. When evaluating the returning traveler with fever, it is important to know which pretravel immunizations the patient received; which medications he ...

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