Dec 15, 2017 Issue
Is "Precision Medicine" Ready to Use in Primary Care Practice? No: It Is Barely Ready for Testing [Editorials: Controversies in Family Medicine]

Precision medicine is ultimately only a tool, and just as it might be used to facilitate better outcomes, if adopted prematurely, it may paradoxically increase inappropriate care. Therefore, primary care physicians must wait for carefully conducted randomized studies to demonstrate benefits before embracing it.

Dec 15, 2017 Issue
Is "Precision Medicine" Ready to Use in Primary Care Practice? Yes: It Offers Patients More Individualized Ways of Managing Their Health [Editorials: Controversies in Family Medicine]

The question that primary care physicians should be considering is not whether precision medicine is ready for “prime time” in their practices. Rather, they should be considering how they will adjust their practice patterns to the changing landscape of medicine to maximize patient benefit while minimizing potential harms, including costs.

Jun 1, 2017 Issue
Expanded Newborn Screening: Information and Resources for the Family Physician [Article]

Each year, 4 to 5 million newborns receive state-mandated screening in an effort to detect and treat serious disorders before harmful effects can occur. Learn about the recommended screening tests and resources for determining the next steps if a newborn screening result is positive.

Feb 15, 2017 Issue
Newborn with an Arm Deformity [Photo Quiz]

A newborn presents with bilateral wrist flexion and shortened forearms.

Jul 15, 2016 Issue
Genetic Test Results That Identify Increased Risk Do Not Change Behavior [POEMs]

Patients informed via genetic test results that they were at increased risk of disease did not subsequently alter their behaviors. For example, persons at increased risk of diabetes mellitus or hypertension were no more likely to change their diet or increase their physical activity. Fancy tests do not appear to be motivators for behavior change.

Dec 1, 2015 Issue
Family History, Social Media, and a Diagnostic Surprise [Close-ups]

Social media and the Internet can be valuable resources for patients, especially for those who have been estranged from their families.

Oct 1, 2015 Issue
Pharmacogenetics: Using Genetic Information to Guide Drug Therapy [Article]

Clinical pharmacogenetics, the use of genetic data to guide drug therapy decisions, is increasingly being used for medications commonly prescribed by family physicians. Two common gene-drug pairs are discussed to illustrate how pharmacogenetic data can be applied clinically.

Oct 1, 2015 Issue
Pharmacogenetic Testing—An Unfulfilled Promise [Editorials]

Family physicians should not naively accept a new technology because it is the latest trend. We need to assess the clinical utility of potential applications of genetic information, adopting them when they improve patient-oriented outcomes and avoiding them when they simply add costs for little to no benefit.

Jan 15, 2015 Issue
Screening for Hereditary Cancer Syndromes [Curbside Consultation]

Family physicians play a key role in identifying patients in need of increased cancer surveillance because of a personal or family history of cancer. How does one know if a patient warrants genetic testing for hereditary cancer predisposition?

Jan 1, 2014 Issue
Noonan Syndrome [Article]

Noonan syndrome is a common genetic disorder that causes multiple congenital abnormalities and a large number of potential health conditions. Most affected individuals have characteristic facial features that evolve with age; a broad, webbed neck; increased bleeding tendency; and a high incidence of...

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