ITEMS IN AFP WITH KEYWORD:
Pharmacogenetics is a growing field of research that focuses on the interaction between genetics and drug therapy. Relationships between genetic variation and drug effect have been observed for a growing number of commonly used drugs. Validation studies may soon define the use of these relationships...
Oct 15, 2007 Issue
ACOG Publishes Guidelines on Hemoglobinopathies in Pregnancy [Practice Guidelines]
The American College of Obstetricians and Gynecologists (ACOG) has released recommendations for screening and clinical management of hemoglobinopathies during pregnancy. The ACOG estimates that more than 270 million persons worldwide are heterozygous carriers of hereditary disorders of hemoglobin (Hb).
Turner syndrome occurs in one out of every 2,500 to 3,000 live female births. The syndrome is characterized by the partial or complete absence of one X chromosome (45,X karyotype). Patients with Turner syndrome are at risk of congenital heart defects (e.g., coarctation of aorta, bicuspid aortic valv...
Jun 1, 2007 Issue
Screening for Hemochromatosis: Recommendation Statement [U.S. Preventive Services Task Force]
This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for hemochromatosis and the supporting scientific evidence.
Nov 15, 2006 Issue
Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility [Putting Prevention into Practice]
Case study: A 46-year-old woman comes to your office to discuss breast cancer screening. She heard a physician on television who mentioned a genetic test that can tell if a woman will get breast cancer.
The American College of Obstetricians and Gynecologists (ACOG) has released recommendations for screening for Tay-Sachs disease.
Mar 15, 2006 Issue
AAP Guidelines on Health Supervision of Patients with Achondroplasia [Practice Guidelines]
The Committee on Genetics of the American Academy of Pediatrics (AAP) has released a clinical report that includes guidelines to help physicians oversee the health of patients with achondroplasia.
Mar 1, 2006 Issue
Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement [U.S. Preventive Services Task Force]
This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility and the supporting scientific evidence.
Current genetic tests for complex diseases are not diagnostic. They instead provide important information about susceptibility and can be key in prevention.
To complement the 2005 Annual Clinical Focus on medical genomics, AFP is publishing a series of short reviews on genetic syndromes. This series was designed to increase awareness of these diseases so that family physicians can recognize and diagnose children with these disorders and understand the k...