May 15, 2017 Issue
Topiramate and Amitriptyline Not Effective for Migraine in Children [POEMs]

Topiramate, amitriptyline, and placebo all led to a similar, substantial improvement in migraine frequency and disability. How to harness this strong placebo effect for our patients is an important, but unanswered, question.

Feb 1, 2017 Issue
AAN Updates Guidelines on the Uses of Botulinum Neurotoxin [Practice Guidelines]

In 2008, the American Academy of Neurology (AAN) published guidelines on the use of botulinum neurotoxin. This summary highlights updates on four indications: blepharospasm, cervical dystonia, spasticity in adults, and headache.

Nov 1, 2016 Issue
Valproate for Adult Migraine Prophylaxis [Medicine by the Numbers]

Evidence supports current guideline recommendations on the use of valproate medications to prevent migraine.

Aug 1, 2016 Issue
Acupuncture for Frequent Tension-Type Headaches [Medicine by the Numbers]

Studies show an NNT of 3 to have at least a 50% reduction of headache frequency compared with routine care. Want to know more?

May 1, 2016 Issue
Ibuprofen for Treatment of Episodic Tension-Type Headaches [Medicine by the Numbers]

Studies show that 1 in 14 patients were parin-free at two hours and none experienced adverse events. Find out more.

Jul 1, 2014 Issue
Topiramate for the Prophylaxis of Episodic Migraine in Adults [Cochrane for Clinicians]

Topiramate in a dosage of 100 mg per day is effective for decreasing the frequency of headaches in adults with episodic migraine.

May 1, 2014 Issue
Gabapentin for the Prophylaxis of Episodic Migraine in Adults [Cochrane for Clinicians]

Gabapentin does not decrease the frequency of migraine headaches and is not recommended for prophylactic therapy.

May 1, 2014 Issue
Acute Migraine Treatment in Emergency Settings [Implementing AHRQ Effective Health Care Reviews]

What are the comparative benefits and adverse effects of parenteral treatments for adults who present to the emergency department with migraine headaches?

Apr 15, 2014 Issue
Chronic Daily Headache: Diagnosis and Management [Article]

What are the most common types and causes, and the most effective treatments?

Feb 1, 2014 Issue
Aspirin With or Without Antiemetic for Acute Migraine Headaches in Adults [Cochrane for Clinicians]

Aspirin, with or without an antiemetic, is an effective treatment for acute migraine headache. Adding the antiemetic metoclopramide (Reglan) significantly reduces migraine-related nausea and vomiting compared with aspirin alone.

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