Heart Disease

Aug 1, 2010 Issue
Evidence for Global CHD Risk Calculation: Risk Assessment Alone Does Not Change Outcomes [Editorials]

To prevent heart attack, stroke, or death, the American Heart Association recommends estimating patients’ absolute risk of having a coronary heart disease (CHD) event in 10 years. Before physicians adopt routine risk calculation, we should use the evidence to determine the best use of our patients’ time and resources.

Jul 15, 2010 Issue
Primary Prevention of CVD: Physical Activity [Clinical Evidence Handbook]

Does counseling to increase physical activity lead to increased physical activity in healthy persons without existing CVD? What are the health benefits of increasing physical activity in relation to cardiovascular outcomes in healthy persons without existing CVD?

Apr 1, 2010 Issue
Effectiveness of B-Complex Vitamins for Prevention of Cardiovascular Events [Cochrane for Clinicians]

Eight randomized clinical trials that included 24,210 patients did not show a reduction in MI, stroke, or all-cause mortality with B-complex vitamin therapy.

Aug 15, 2009 Issue
Acute Coronary Syndrome (Unstable Angina and non-ST Elevation Myocardial Infarction) [Clinical Evidence Handbook]

What are the effects of antiplatelet, antithrombin, anti-ischemic, and lipid-lowering treatments in persons with acute coronary syndrome? What are the effects of invasive treatments?

May 15, 2009 Issue
AHA Releases Recommendations on Cardiovascular Monitoring and the Use of ADHD Medications in Children with Heart Disease [Practice Guidelines]

The American Heart Association (AHA) has released a scientific statement and recommendations about cardiovascular monitoring and the use of stimulants in children suspected or known to have heart disease.

Apr 1, 2009 Issue
Heparins for Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction [Cochrane for Clinicians]

Compared with standard therapy with aspirin, the use of heparin does not reduce mortality, the need for revascularization, and recurrent angina. Heparin does reduce the occurrence of myocardial infarction (MI; number needed to treat [NNT] = 33), defined as “typical chest pain associated with the app...

Mar 15, 2009 Issue
The JUPITER Study: Biomarkers Plus Statin vs. Lifestyle Modification for Preventing Cardiovascular Events [Editorials]

Apr 15, 2007 Issue
Noninvasive Cardiac Imaging [Article]

Noninvasive cardiac imaging can be used for the diagnostic and prognostic assessment of patients with suspected or known coronary artery disease. It is central to the treatment of patients with myocardial infarction, coronary artery disease, or acute coronary syndromes with or without angina. Radion...

Apr 1, 2007 Issue
AHA Publishes Guidelines on CVD Prevention in Women [Practice Guidelines]

Guidelines presented by the American Heart Association (AHA) represent the most current clinical recommendations for the prevention of cardiovascular disease (CVD) in women 20 years and older.

Feb 15, 2007 Issue
Ranolazine (Ranexa) for Chronic Angina [STEPS]

Ranolazine will provide a small benefit in symptom control in patients with chronic angina and persistent symptoms despite medical therapy. It generally should be used in combination with amlodipine, beta blockers, or long-acting nitrates.

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