Heart Disease

Apr 1, 2009 Issue
Heparins for Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction [Cochrane for Clinicians]

Compared with standard therapy with aspirin, the use of heparin does not reduce mortality, the need for revascularization, and recurrent angina. Heparin does reduce the occurrence of myocardial infarction (MI; number needed to treat [NNT] = 33), defined as “typical chest pain associated with the app...

Mar 15, 2009 Issue
The JUPITER Study: Biomarkers Plus Statin vs. Lifestyle Modification for Preventing Cardiovascular Events [Editorials]

Apr 15, 2007 Issue
Noninvasive Cardiac Imaging [Article]

Noninvasive cardiac imaging can be used for the diagnostic and prognostic assessment of patients with suspected or known coronary artery disease. It is central to the treatment of patients with myocardial infarction, coronary artery disease, or acute coronary syndromes with or without angina. Radion...

Apr 1, 2007 Issue
AHA Publishes Guidelines on CVD Prevention in Women [Practice Guidelines]

Guidelines presented by the American Heart Association (AHA) represent the most current clinical recommendations for the prevention of cardiovascular disease (CVD) in women 20 years and older.

Feb 15, 2007 Issue
Ranolazine (Ranexa) for Chronic Angina [STEPS]

Ranolazine will provide a small benefit in symptom control in patients with chronic angina and persistent symptoms despite medical therapy. It generally should be used in combination with amlodipine, beta blockers, or long-acting nitrates.

Jan 1, 2007 Issue
Early Invasive Therapy or Conservative Management for Unstable Angina or NSTEMI? [Cochrane for Clinicians]

Compared with conservative management, early invasive treatment of patients with UA or NSTEMI using coronary angiography with or without revascularization reduces rehospitalization and refractory angina within the first year and significantly reduces mortality and myocardial infarction at two to fiv...

May 1, 2006 Issue
Dietary Advice to Lower Cardiovascular Risk [Cochrane for Clinicians]

Dietary advice to lower fat and salt intake and increase intake of fruits, vegetables, and fiber produces modest improvements in cardiovascular risk factors. More intensive counseling yields greater effects.

Mar 15, 2006 Issue
AHA Evaluates Exercise Testing as a Screening Tool in Asymptomatic Patients [Practice Guidelines]

The Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention of the American Heart Association (AHA) has released a scientific statement on exercise testing to screen asymptomatic patients for disease.

Mar 15, 2006 Issue
Amlodipine/Atorvastin (Caduet) for Preventing Heart Disease [STEPS]

Amlodipine/atorvastatin offers no added benefit in safety, tolerability, or effectiveness over amlodipine and atorvastatin taken separately. It has not been shown to improve mortality or morbidity in patients who have hypertension with or without dyslipidemia. The only potential advantages to amlodi...

Oct 1, 2005 Issue
Does a Low Glycemix Index Diet Reduce CHD? [Cochrane for Clinicians]

There is limited, weak evidence that a low glycemic index diet improves risk factors for CHD, but there are no randomized controlled trials (RCTs) showing a reduction in morbidity or mortality.

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