Heart Failure

Apr 1, 2008 Issue
Pharmacologic Management of Heart Failure Caused by Systolic Dysfunction [Article]

Heart failure caused by systolic dysfunction affects more than 5 million adults in the United States and is a common source of outpatient visits to primary care physicians. Mortality rates are high, yet a number of pharmacologic interventions may improve outcomes. Other interventions, including pati...

Apr 15, 2007 Issue
Predicting Mortality Risk in Patients with Acute Exacerbations of Heart Failure [Point-of-Care Guides]

Accurate risk stratification in patients with heart failure can help physicians choose the most appropriate place for hospitalization (general hospital ward or intensive care unit) and the intensity of care needed.

Mar 1, 2007 Issue
Diagnosis and Management of Chronic Heart Failure in Adults [Practice Guidelines]

Changes in the diagnosis and management of chronic heart failure in adults are reflected in updated guidelines from the American College of Cardiology (ACC) and American Heart Association (AHA).

Feb 1, 2007 Issue
AHRQ Evaluates Peptides as Determinants for Patients with Heart Failure [Practice Guidelines]

B-type natriuretic peptide (BNP) and N-terminal pro-hormone brain natriuretic peptide (NT-proBNP) are markers for heart failure diagnosis, prognosis, and treatment. The Agency for Healthcare Research and Quality (AHRQ) systematically reviewed available literature to further study these peptides.

Dec 1, 2006 Issue
The Role of BNP Testing in Heart Failure [Article]

Brain natriuretic peptide (BNP) levels are simple and objective measures of cardiac function. These measurements can be used to diagnose heart failure, including diastolic dysfunction, and using them has been shown to save money in the emergency department setting. The high negative predictive value...

Aug 15, 2006 Issue
Digoxin Therapy for Heart Failure: An Update [Article]

Digoxin therapy has long been used to treat heart failure; however, its effectiveness was not completely known until recently. Results of the Digitalis Investigation Group trial showed that adding digoxin to standard heart failure therapy had no effect on mortality. However, adding digoxin decreased...

Aug 1, 2006 Issue
Diuretics for Treatment of Patients with Heart Failure? [Cochrane for Clinicians]

Compared with other active medications, diuretics can improve exercise capacity in patients with heart failure by about 30 percent. Withdrawal of diuretic therapy from patients with heart failure may increase the risk of hospital readmission or death. About eight deaths are prevented for every 100 patients treated.

Aug 1, 2006 Issue
Heart Failure [Clinical Evidence Handbook]

What are the effects of nondrug, drug and invasive treatments? What are the effects of ACE inhibitors in persons at high risk of heart failure?

Mar 1, 2006 Issue
Diagnosis and Management of Diastolic Dysfunction and Heart Failure [Article]

Diastolic heart failure occurs when signs and symptoms of heart failure are present but left ventricular systolic function is preserved (i.e., ejection fraction greater than 45 percent). The incidence of diastolic heart failure increases with age; therefore, 50 percent of older patients with heart f...

Feb 15, 2006 Issue
Nesiritide (Natrecor) for Acute Decompensated Heart Failure [STEPS]

Nesiritide improves short-term hemodynamics in hospitalized patients with acute decompensated heart failure who have not benefited from aggressive treatment with standard care. However, nesiritide may cause renal function to worsen and may increase the risk of death within 30 days.

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