Heart Failure

Aug 1, 2006 Issue
Diuretics for Treatment of Patients with Heart Failure? [Cochrane for Clinicians]

Compared with other active medications, diuretics can improve exercise capacity in patients with heart failure by about 30 percent. Withdrawal of diuretic therapy from patients with heart failure may increase the risk of hospital readmission or death. About eight deaths are prevented for every 100 patients treated.

Aug 1, 2006 Issue
Heart Failure [Clinical Evidence Handbook]

What are the effects of nondrug, drug and invasive treatments? What are the effects of ACE inhibitors in persons at high risk of heart failure?

Mar 1, 2006 Issue
Diagnosis and Management of Diastolic Dysfunction and Heart Failure [Article]

Diastolic heart failure occurs when signs and symptoms of heart failure are present but left ventricular systolic function is preserved (i.e., ejection fraction greater than 45 percent). The incidence of diastolic heart failure increases with age; therefore, 50 percent of older patients with heart f...

Feb 15, 2006 Issue
Nesiritide (Natrecor) for Acute Decompensated Heart Failure [STEPS]

Nesiritide improves short-term hemodynamics in hospitalized patients with acute decompensated heart failure who have not benefited from aggressive treatment with standard care. However, nesiritide may cause renal function to worsen and may increase the risk of death within 30 days.

Jul 1, 2005 Issue
Which Patients Benefit from CRT? [Practice Guidelines]

The American Heart Association has published a science advisory on selecting patients for cardiac resynchronization therapy (CRT).

Dec 1, 2004 Issue
Outpatient Treatment of Systolic Heart Failure [Article]

Optimal outpatient treatment of systolic heart failure has three goals that should be pursued simultaneously: (1) control of risk factors for the development and progression of heart failure, (2) treatment of heart failure, and (3) education of patients. Control of risk factors includes treating hyp...

Dec 1, 2004 Issue
Diagnosis of Heart Failure in Adults [Article]

Heart failure is a common, progressive, complex clinical syndrome with high morbidity and mortality. Coronary artery disease is its most common cause. The evaluation of symptomatic patients with suspected heart failure is directed at confirming the diagnosis, determining the cause, identifying conco...

Jun 1, 2004 Issue
Diastolic Heart Failure: The Challenges of Diagnosis and Treatment [Article]

Diastolic heart failure, a major cause of morbidity and mortality, is defined as symptoms of heart failure in a patient with preserved left ventricular function. It is characterized by a stiff left ventricle with decreased compliance and impaired relaxation, which leads to increased end diastolic pr...

Jan 1, 2004 Issue
Digitalis for Treatment of Congestive Heart Failure in Patients in Sinus Rhythm [Cochrane for Clinicians]

Adding digitalis to treatment with angiotensin-converting enzyme (ACE) inhibitors and diuretics will reduce hospitalization rates and improve clinical status in patients in normal sinus rhythm with left ventricular systolic dysfunction (LVSD) and symptoms of CHF on moderate or mild exertion (New Yor...

Nov 1, 2003 Issue
Combination Therapy with ACE Inhibitors and Angiotensin-Receptor Blockers in Heart Failure [Article]

Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers have different pharmacologic mechanisms for blocking the effect of the renin-angiotensin-aldosterone system on the cardiovascular system. Pharmacologically, the combination of these drug classes completely blocks the deleteri...

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