Hematologic Disorders

Aug 1, 2019 Issue
Hematologic Abnormality in a Young Soldier [Photo Quiz]

Feb 15, 2016 Issue
Clinical Evaluation of Bleeding and Bruising in Primary Care [Article]

Find out what to look for in the patient history and physical examination, which medications can cause abnormal bleeding and bruising, how to interpret laboratory results, and when to refer patients to a hematologist.

Dec 1, 2015 Issue
Evaluation of Patients with Leukocytosis [Article]

Review the types of white blood cells, the most common malignant and nonmalignant causes of leukocytosis, and the key examination and laboratory findings to determine the etiology.

Mar 15, 2012 Issue
Thrombocytopenia [Article]

Thrombocytopenia is defined as a platelet count of less than 150 × 103 per µL. It is often discovered incidentally when obtaining a complete blood count during an office visit. The etiology usually is not obvious, and additional investigation is required. Patients with platelet counts greater than 5...

Dec 15, 2009 Issue
Nonhealing Diaper Rash with Associated Hepatosplenomegaly [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

Dec 1, 2009 Issue
Diagnosis and Management of Von Willebrand Disease: Guidelines for Primary Care [Article]

Von Willebrand disease is an inherited condition characterized by deficiency of von Willebrand factor, which is essential in hemostasis. The National Heart, Lung, and Blood Institute has released new evidence-based guidelines for the diagnosis and management of the disease. There are three major sub...

Aug 15, 2009 Issue
Alpha and Beta Thalassemia [Article]

The thalassemias are a group of inherited hematologic disorders caused by defects in the synthesis of one or more of the hemoglobin chains. Alpha thalassemia is caused by reduced or absent synthesis of alpha globin chains, and beta thalassemia is caused by reduced or absent synthesis of beta globin ...

Sep 15, 2006 Issue
Hemolytic Uremic Syndrome: An Emerging Health Risk [Article]

Hemolytic uremic syndrome is caused primarily by Shiga toxin-producing Escherichia coli O157:H7. The most common cause of acute renal failure in children, hemolytic uremic syndrome also can occur in adults. Characteristic features of the syndrome are microangiopathic anemia, thrombotic thrombocytope...

May 1, 2004 Issue
Polycythemia Vera [Article]

Polycythemia vera is a chronic myeloproliferative disorder characterized by increased red blood cell mass. The resultant hyperviscosity of the blood predisposes such patients to thrombosis. Polycythemia vera should be suspected in patients with elevated hemoglobin or hematocrit levels, splenomegaly,...

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