Apr 15, 2014 Issue
Screening for HIV: Recommendation Statement [U.S. Preventive Services Task Force]

The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians screen for human immunodeficiency virus (HIV) infection in adolescents and adults 15 to 65 years of age. Younger adolescents and older adults who are at increased risk should also be screened.

Apr 15, 2014 Issue
Screening for HIV [Putting Prevention into Practice]

A 19-year-old woman presents to the university health clinic for a well-woman examination. She reports no problems and mentions that she is sexually active with one male partner, who usually uses condoms. She has never been screened for a sexually transmitted infection.

Apr 15, 2014 Issue
AAFP Recommends Universal Screening for HIV Infection Beginning at 18 Years of Age [Editorials]

The AAFP recommends delaying the start of routine HIV screening until 18 years of age, and screening all patients 18 to 65 years of age. The AAFP notes that screening younger patients may still be beneficial based on high-risk behaviors.

Feb 15, 2014 Issue
What Is New in HIV Infection? [Article]

Human immunodeficiency virus (HIV) prevention and treatment updates include screening recommendations, fourth-generation testing, preexposure prophylaxis, and a paradigm shift; treatment is prevention. The U.S. Preventive Services Task Force recommends routine HIV screening in persons 15 to 65 years...

Oct 15, 2013 Issue
Emtricitabine/Tenofovir (Truvada) for HIV Prophylaxis [STEPS]

When used with a comprehensive HIV prevention strategy, emtricitabine/tenofovir effectively prevents HIV-1 infection in high-risk patients. Adherence to daily dosing is important to maintain protection. The cost of therapy may limit access, and not all insurance companies currently cover its use for HIV prophylaxis.

Aug 1, 2013 Issue
Antiretroviral Preexposure Prophylaxis for Preventing HIV Infection in High-Risk Individuals [Cochrane for Clinicians]

For some groups of patients at greater risk of HIV infection (e.g., serodiscordant partners, men who have sex with men and engage in high-risk behaviors, persons with multiple concurrent sex partners, persons who exchange sex for money), preexposure prophylaxis decreased the risk of acquiring HIV infection (number needed to treat [NNT] = 56).

Jul 15, 2013 Issue
Corticosteroids for Presumed Pneumocystis Pneumonia in Patients with HIV Infection [FPIN's Clinical Inquiries]

Adjunctive corticosteroids decrease mortality in patients with HIV infection who have moderate to severe hypoxemia and suspected or confirmed pneumocystis pneumonia. Corticosteroids lead to a higher incidence of herpetic lesions, but not other opportunistic conditions.

Mar 1, 2012 Issue
Antiretroviral Therapy to Prevent Transmission in HIV-Discordant Couples [Cochrane for Clinicians]

Rates of HIV transmission are at least three times lower in HIV-discordant couples in which the partner with infection is receiving antiretroviral therapy, compared with HIV-discordant couples in which the partner with infection is not receiving therapy. Among HIV-discordant couples in which the inf...

Jun 15, 2011 Issue
Common Adverse Effects of Antiretroviral Therapy for HIV Disease [Article]

Family physicians are treating patients infected with human immunodeficiency virus in their practices more often. Long-term complications of this disease are multifactorial and can be related to the virus itself or to adverse effects of antiretroviral therapy. Each drug class has side effects: nucle...

Feb 15, 2011 Issue
Complications of HIV Infection: A Systems-Based Approach [Article]

Patients with human immunodeficiency virus (HIV) infection often develop multiple complications and comorbidities. Opportunistic infections should always be considered in the evaluation of symptomatic patients with advanced HIV/AIDS, although the overall incidence of these infections has decreased. ...

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