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Feb 15, 2015 Issue
Screening for Primary Hypertension in Children and Adolescents [Putting Prevention into Practice]
L.S. is a 14-year-old black adolescent who presents for a routine school physical examination. Her mother tells you that she and her husband have hypertension, and they worry about their daughter's blood pressure. She asks you whether L.S. should be periodically checked for high blood pressure.
Feb 1, 2015 Issue
Angiotensin-Converting Enzyme Inhibitors vs. Angiotensin Receptor Blockers [FPIN's Clinical Inquiries]
ACE inhibitors should be used in patients with hypertension because they reduce all-cause mortality, whereas ARBs do not.
Find out what the JNC 8 recommendations changed regarding whom to treat, goal blood pressures, nonpharmacologic treatment, and preferred drug classes for different patient populations.
Oct 1, 2014 Issue
JNC8 Guidelines for the Management of Hypertension in Adults [Practice Guidelines]
Hypertension is one of the most important preventable contributors to disease and death in the United States, leading to myocardial infarction, stroke, and renal failure when it is not detected early and treated appropriately. The Eighth Joint National Committee (JNC 8) recently released evidence-ba...
The Eighth Joint National Committee (JNC 8) recently issued the most anticipated hypertension guideline in some time. The most significant change in the JNC 8 guideline is relaxation of the systolic and diastolic blood pressure goals for adults 60 years and older. As a result of the new guidelines, ...
Aspirin does not elevate blood pressure. Among nonselective NSAIDs, ibuprofen increases the risk of hypertension and stroke. Diclofenac does not increase the risk of hypertension, but does increase the risk of stroke. Naproxen (Naprosyn) does not increase the risk of hypertension or stroke. Celecoxi...
See the Synopsis section for a summary of the updated hypertension treatment recommendations from the Eighth Joint National Committee (JNC 8).
It seems to be safe to lower systolic blood pressure to a target of 140 mm Hg in those with an acute hemorrhagic stroke. However, there seems to be no clinical benefit to this approach when the data are adjusted for baseline NIH Stroke Scale scores.
Vitamin D supplementation in patients with isolated systolic hypertension and low levels of vitamin D does not decrease systolic blood pressure after one year of treatment.
In this retrospective analysis, chlorthalidone and HCTZ produced the same clinical outcomes in older adults. In general, chlorthalidone was more likely to be associated with hospitalization for hypokalemia and hyponatremia. When comparing equivalent doses, though, the rates of these adverse effects were the same.