Oct 1, 2014 Issue
JNC 8: Relaxing the Standards [Editorials]

The Eighth Joint National Committee (JNC 8) recently issued the most anticipated hypertension guideline in some time. The most significant change in the JNC 8 guideline is relaxation of the systolic and diastolic blood pressure goals for adults 60 years and older. As a result of the new guidelines, ...

Aug 15, 2014 Issue
Cardiovascular Effects of NSAIDs [FPIN's Clinical Inquiries]

Aspirin does not elevate blood pressure. Among nonselective NSAIDs, ibuprofen increases the risk of hypertension and stroke. Diclofenac does not increase the risk of hypertension, but does increase the risk of stroke. Naproxen (Naprosyn) does not increase the risk of hypertension or stroke. Celecoxi...

Apr 1, 2014 Issue
JNC 8 Report on Prevention, Evaluation, and Treatment of Hypertension [POEMs]

See the Synopsis section for a summary of the updated hypertension treatment recommendations from the Eighth Joint National Committee (JNC 8).

Jan 15, 2014 Issue
Is Intensive Blood Pressure Control Beneficial in Patients with Acute Intracerebral Hemorrhage? [AFP Journal Club]

It seems to be safe to lower systolic blood pressure to a target of 140 mm Hg in those with an acute hemorrhagic stroke. However, there seems to be no clinical benefit to this approach when the data are adjusted for baseline NIH Stroke Scale scores.

Dec 1, 2013 Issue
Vitamin D Does Not Affect Isolated Systolic Hypertension [POEMs]

Vitamin D supplementation in patients with isolated systolic hypertension and low levels of vitamin D does not decrease systolic blood pressure after one year of treatment.

Oct 15, 2013 Issue
Same Benefit with Equivalent Doses of Chlorthalidone and HCTZ [POEMs]

In this retrospective analysis, chlorthalidone and HCTZ produced the same clinical outcomes in older adults. In general, chlorthalidone was more likely to be associated with hospitalization for hypokalemia and hyponatremia. When comparing equivalent doses, though, the rates of these adverse effects were the same.

Jul 1, 2013 Issue
Pharmacotherapy for Mild Hypertension [Cochrane for Clinicians]

Pharmacologic treatment of mild hypertension for up to five years does not reduce coronary events, stroke, or mortality compared with placebo.

Apr 1, 2013 Issue
Effect of Cocoa on Blood Pressure [Cochrane for Clinicians]

Consuming 50 g of cocoa daily will lower blood pressure 2 to 3 mm Hg on average in adults with hypertension. Evidence of improved patient-oriented outcomes does not exist.

Jul 15, 2012 Issue
The "ARB-MI Paradox": Real or a Fluke? [AFP Journal Club]

The Journal Club authors discuss what factors make this meta-analysis, designed to determine whether the ARB-MI paradox is real or a statistical fluke, successful.

Apr 1, 2012 Issue
High Blood Pressure in Children and Adolescents [Article]

High blood pressure in children and adolescents is a growing health problem that is often overlooked by physicians. Normal blood pressure values for children and adolescents are based on age, sex, and height, and are available in standardized tables. Prehypertension is defined as a blood pressure in...

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