Immune Disorders

Dec 15, 2011 Issue
Antibody Testing for Systemic Lupus Erythematosus [FPIN's Clinical Inquiries]

Antibody testing plays an important role when assessing patients, but should not be used alone to diagnose SLE.

Nov 15, 2011 Issue
Patient with Plaques on Lower Extremities and Systemic Symptoms [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

Jul 15, 2011 Issue
Blistering Eruption on the Leg of an Adult [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

Mar 1, 2011 Issue
Systemic Vasculitis [Article]

The systemic vasculitides are characterized by inflammation of blood vessel walls. Vessels of any type, in any organ can be affected, resulting in a broad spectrum of signs and symptoms. The heterogenous nature of vasculitides presents a diagnostic challenge. The American College of Rheumatology cla...

Oct 1, 2009 Issue
Henoch-Schönlein Purpura [Article]

Henoch-Schönlein purpura is an acute, systemic, immune complex-mediated, leukocytoclastic vasculitis. It is characterized by a triad of palpable purpura (without thrombocytopenia), abdominal pain, and arthritis. Most patients have an antecedent upper respiratory illness. More than 90 percent of Hen...

Mar 15, 2009 Issue
Diagnosis and Management of Sjogren Syndrome [Article]

Sjogren syndrome is a systemic autoimmune disease characterized by dry eyes and dry mouth. Other organ systems are affected in many patients. Sjogren syndrome is classified as primary or secondary. In primary disease, Sjogren syndrome is a solitary process, whereas secondary disease accompanies anot...

Oct 15, 2008 Issue
Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease [Article]

Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. Raynaud phenomenon and scleroderma (hardening of the skin) are hallmarks of the disea...

Nov 1, 2007 Issue
Systemic Lupus Erythematosus [Clinical Evidence Handbook]

What are the effects of treatments on joint (arthralgia and arthritis) symptoms and other nonorgan-threatening symptoms such as serositis and fatigue in persons with systemic lupus erythematosus (SLE)? What are the effects of interventions for cutaneous involvement in persons with SLE? What are the ...

Mar 1, 2007 Issue
Autoimmune Polyendocrine Syndrome, Type II [Article]

The combination of autoimmune adrenal insufficiency with autoimmune thyroid disease and/or type 1 autoimmune diabetes mellitus defines autoimmune polyglandular syndrome, type II. The conditions may occur in any order, and diagnosis is confounded by the nonspecific nature of the symptoms of adrenal i...

May 15, 2006 Issue
A Swelling in the Neck [Photo Quiz]

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

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