Infectious Disease, Bacterial

Dec 01, 2021 Issue
Neonatal Early-Onset Sepsis Calculator [Point-of-Care Guides]

Can the neonatal early-onset sepsis calculator safely and accurately evaluate the risk of early-onset sepsis in neonates?

Oct 01, 2021 Issue
Diabetes-Related Foot Infections: Diagnosis and Treatment [Article]

Diabetes-related foot infections occur in approximately 40% of diabetes-related foot ulcers and cause significant morbidity. Clinicians should consider patient risk factors (e.g., presence of foot ulcers greater than 2 cm, uncontrolled diabetes mellitus, poor vascular perfusion, comorbid illness) wh...

Sep 01, 2021 Issue
Applying a Clinical Prediction Rule to Distinguish Lower Extremity Cellulitis from Its Mimics [Point-of-Care Guides]

How can the clinician best determine whether a patient with lower leg erythema has cellulitis?

Aug 01, 2021 Issue
Pertussis: Common Questions and Answers [Article]

Pertussis, also known as whooping cough, remains a public health concern despite expanded immunization recommendations over the past three decades. The presentation of pertussis, which is variable and evolves over the course of the disease, includes nonspecific symptoms in the catarrhal stage, cough...

Jul 15, 2020 Issue
Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: Recommendation Statement [U.S. Preventive Services Task Force]

The USPSTF recommends against screening for bacterial vaginosis in pregnant persons who are not at increased risk for preterm delivery.

Jun 15, 2020 Issue
Ozenoxacin (Xepi) for the Treatment of Impetigo [STEPS]

Ozenoxacin is an effective and safe topical quinolone treatment for bullous and nonbullous impetigo in patients as young as two months. However, it is expensive and some patients may have limited access because it is only available through a physician or hospital.

May 1, 2020 Issue
Tickborne Diseases: Diagnosis and Management [Article]

The incidence of tickborne disease is increasing in the United States. Patients presenting with flulike symptoms during the spring and summer months should be evaluated for a tickborne disease. Treatment based on experience and observation is recommended for tickborne diseases that fit the clinical presentation and geographic distribution of the disease. Early treatment with doxycycline has been shown to improve morbidity and mortality. Prophylactic treatment after tick exposure in patients without symptoms is generally not recommended.

Apr 15, 2020 Issue
Screening for Asymptomatic Bacteriuria in Adults: Recommendation Statement [U.S. Preventive Services Task Force]

The USPSTF recommends screening for asymptomatic bacteriuria using urine culture in pregnant persons. The USPSTF recommends against screening for asymptomatic bacteriuria in nonpregnant adults.

Apr 15, 2020 Issue
Screening for Asymptomatic Bacteriuria in Adults [Putting Prevention into Practice]

A 33-year-old woman presents to your clinic for a first prenatal visit at 8 weeks' gestation. She reported morning nausea and breast tenderness. Review of systems and physical examination were consistent with early pregnancy but were otherwise unremarkable.

Apr 1, 2020 Issue
Sepsis: Diagnosis and Management [Article]

To improve sepsis diagnosis, which can be challenging, clinicians must obtain historical, clinical, laboratory, and radiographic data supportive of infection and organ dysfunction. After initial airway and respiratory stabilization, the sepsis bundle should be initiated (fluid resuscitation, antibiotics, lactate measurement, and cultures) within three hours of presentation. Vasopressor therapy is needed if fluid resuscitation is ineffective.

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