Kidney Disorders

Oct 1, 2009 Issue
Gadolinium-Associated Nephrogenic Systemic Fibrosis [Article]

Nephrogenic systemic fibrosis is a progressive, potentially fatal multiorgan system fibrosing disease related to exposure of patients with renal failure to the gadolinium-based contrast agents used in magnetic resonance imaging. Because of this relationship between nephrogenic systemic fibrosis and ...

Sep 15, 2008 Issue
Drug-Induced Nephrotoxicity [Article]

Drugs are a common source of acute kidney injury. Compared with 30 years ago, the average patient today is older, has more comorbidities, and is exposed to more diagnostic and therapeutic procedures with the potential to harm kidney function. Drugs shown to cause nephrotoxicity exert their toxic eff...

Aug 15, 2007 Issue
CDC Reports on Racial Differences in Patients with ESRD [Practice Guidelines]

The Centers for Disease Control and Prevention (CDC) has released a report on the racial differences in patients with end-stage renal disease (ESRD).

May 15, 2007 Issue
Drug Dosing Adjustments in Patients with Chronic Kidney Disease [Article]

Chronic kidney disease affects renal drug elimination and other pharmacokinetic processes involved in drug disposition (e.g., absorption, drug distribution, nonrenal clearance [metabolism]). Drug dosing errors are common in patients with renal impairment and can cause adverse effects and poor outcom...

May 1, 2007 Issue
Nonpharmacologic vs. Anticholinergic Therapies for Overactive Bladder [Cochrane for Clinicians]

Anticholinergic medications are more effective than bladder training in reducing the number of voids per day. Combining an anti-cholinergic medication with bladder training is more effective than either therapy alone.

Apr 15, 2007 Issue
Indications for Renal Arteriography at the Time of Coronary Arteriography [Practice Guidelines]

A science advisory published by American Heart Association (AHA) describes the indications for renal arteriography. When possible, patients with a clinical indication for investigation of renal artery stenosis should undergo noninvasive diagnostic tests before coronary arteriography.

Sep 15, 2006 Issue
Hemolytic Uremic Syndrome: An Emerging Health Risk [Article]

Hemolytic uremic syndrome is caused primarily by Shiga toxin-producing Escherichia coli O157:H7. The most common cause of acute renal failure in children, hemolytic uremic syndrome also can occur in adults. Characteristic features of the syndrome are microangiopathic anemia, thrombotic thrombocytope...

Jul 1, 2006 Issue
Medical Management of Common Urinary Calculi [Article]

Nephrolithiasis is a common condition affecting nearly 5 percent of U.S. men and women during their lifetimes. Recurrent calculi can be prevented in most patients by the use of a simplified evaluation, reasonable dietary and fluid recommendations, and directed pharmacologic intervention. Serum studi...

Nov 1, 2005 Issue
Detection and Evaluation of Chronic Kidney Disease [Article]

Chronic kidney disease affects approximately 19 million adult Americans, and its incidence is increasing rapidly. Diabetes and hypertension are the underlying causes in most cases of chronic kidney disease. Evidence suggests that progression to kidney failure can be delayed or prevented by controlli...

Nov 1, 2005 Issue
Management of Acute Renal Failure [Article]

Acute renal failure is present in 1 to 5 percent of patients at hospital admission and affects up to 20 percent of patients in intensive care units. The condition has prerenal, intrarenal, and postrenal causes, with prerenal conditions accounting for 60 to 70 percent of cases. The cause of acute ren...

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